Prosci/Apo-SAA1重组蛋白/40-134/0.01 mg

价格
¥3100.00
货号:40-134
浏览量:127
品牌:ProSci
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商品描述

Specifications

SPECIES:Human
SOURCESPECIES:E.coli
SEQUENCE:MRSFFSFLGEAFDGARDMWRAYSDMREANYIGSDKYFHARGNYDAAKRGPGGVWAAEAISDARENIQRFFGHGAEDSLADQAANEWGRSGKDPNHFRPAGLPEKY
BIOLOGICALACTIVITY:DeterminedbyitsABIlitytochemoattracthumanmonocytesusingaconcentrationrangeof10.0-10.0ng/mL.

Properties

PURITY:Greaterthan98%bySDS-PAGEgelandHPLCanalyses.

Endotoxinlevelislessthan0.1ngperμg(1EU/μg).
PHYSICALSTATE:Lyophilized
STORAGECONDITIONS:ThelyophilizedApo-SAA1recombinantproteinisstableforatleast2yearsfromdateofreceiptat-20˚C.ReconstitutedApo-SAA1isstableforatleast3monthswhenstoredinworkingaliquotswithacarrierproteinat-20˚C.Aswithanyprotein,exposingApo-SAA1recombinantproteintorepeatedfreeze/thawcyclesisnotrecommended.Whenworkingwithproteinscareshouldbetakentokeeprecombinantproteinatacoolandstabletemperature.

AdditionalInfo

ALTERNATENAMES:SAA,PIG4,SAA2,TP53I4,SerumamyloidA-1protein,AmyloidfibrilproteinAA,SAA
ACCESSIONNO.:NP_000322.2
PROTEINGINO.:40316912

Background

SerumamyloidAproteins(SAA)representsafamilyofapolipoproteinsthatcirculatesinassociationwithhigh-densitylipoproteins(HDL).Thelevelofapo-SAA,normally1-5μg/mLinplasma,increases500-1000foldwithin24hoursofaninflammatorystimulusand,undertheseconditions,isthemostabundantHDLapo-lipoprotein.ThehumanSAAgenecodesfora122aminoacidnonglycosylatedpolypeptide,whichcontainsan18aminoacidN-terminalsequence.Recombinanthumanapo-SAA1isan11.7kDaproteincontaining105aminoacidresidues.
ProSci 研究计划包括癌症生物标记物发现和中和针对新兴病毒(例如HIV和流感)的抗体开发。ProSci的创新方法研究使用基因工程酵母菌株和糖蛋白模拟HIV-1聚糖衣壳并开发针对HIV-1聚糖的中和抗体,已获得NIH的多项小型企业创新研究(SBIR)资助。其研究项目已获得美国专利商标局授予的发明专利,以及许多同行评审的出版物