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Biotinlabeleddideoxyguanosinetriphosphate(ddUTP)isBIOLOGicallyactiveandcanbeincorporatedwithavarietyofDNApolymerasesincludingTaq,Klenowfragment,andSequenase™.ItterminatesfurtherincorporationandenablesidentificationofthecomplementarybaseforapplicationslikeDNAsequencinganddetectionofpointmutations.Biotin-labeledproductsmaybedetectedwithstreptavidinconjugates.Forthehighestsensitivityindetection,werecommendusingastreptavidin-HRPconjugatewithtyramidesignalamplification(TSA).
Thenumber“11”inthecompoundnamereferstothelengthofthelinkerarmbetweenddGTPandthelabel.


