Details:
Tested Applications	WB, ELISA
Target Information	GFAP is a 49.9kDa neural protein expressed in astrocytes
Product Format	Affinity purified
Alternate Names	Glial fibrillary acidic protein
Clone	Set of three: 11A7G10C9, 19F9H6D6, 15C7D5D2
Host	Mouse
Isotype	IgG1
Immunogen	Recombinant protein
Epitope	Unknown
Relevance	GFAP is an intermediate filament protein coexpressed with vimentin in mature astrocytes. Intermediate filaments (IFs), together with microtubules and microfilaments, form an interconnected network of the cytoskeleton, which gives cells their form, shape and functions. This gene encodes one of the major intermediate filament proteins of mature astrocytes. It is used as a marker to distinguish astrocytes from other glial cells during development. Mutations in this gene cause Alexander disease, a rare disorder of astrocytes in the central nervous system. The appearance of GFAP breakdown products in serum and CSF have been linked to TBI, Traumatic Brain Injury.
Specificity	Human GFAP
Reported Reactivity	Unknown
Reported Applications	Unknown

What's Happening at NeoClone Biotechnology You're probably wondering, "Now that BioLegend owns all your former catalog products, what the heck are you doing up there in Madison?" I'm glad you asked. We're still making great monoclonal antibodies, of course! NeoClone has been making custom murine antibodies via hybridoma technology for years. In fact, that's where our catalog came from in the first place! We decided that we needed to return our focus to custom projects, especially the really difficult targets that researchers had been bringing us all along. You know, the targets that other companies couldn't make due to problems with tolerance or toxicity or bizarre secondary structures. Then we decided to branch out into other methods of generating antibodies. We brought on new staff with years of experience in Antibody Phage Display and Camelid VHH antibodies. We've been upping our game in the Bioinformatics arena as well, giving us an edge in determining the best way to make YOUR antibody. Unlike other antibody development companies, we're not tied to one particular method. In the world of antibody development, one size does NOT fit all. So, you tell us what you want. We'll make sure we get it for you.