Description
Enniatins are a group of mycotoxins produced by several fungal species. They are cyclic hexadepsipeptides structurally related to beauvericin. They may be found as contaminants in food commodities, particularly in cereal grains. Enniatins are found to have a variety of biological activities including insecticidal, antifungal, antibiotic and cytotoxic properties. They have been shown to induce apoptosis in several human cancer cell lines and are gaining interest as potential anticancer drugs.
References
Liuzzi VC, Mirabelli V, Cimmarusti MT, et al. Enniatin and beauvericin biosynthesis in Fusarium species: production profiles and structural determinant prediction. Toxins (Basel). 2017 Feb;9(2):45. PMID: 28125067.
Gunter AB, Hermans A, Bosnich W, et al. Protein engineering of Saccharomyces cerevisiae transporter Pdr5p identifies key residues that impact Fusarium mycotoxin export and resistance to inhibition. Microbiologyopen. 2016 Dec;5(6):979-991. PMID: 27263049.
Nazari F, Sulyok M, Kobarfard F, et al. Evaluation of emerging mycotoxins beauvericin, enniatins, fusaproliferin and moniliformin in domestic rice in Iran. Iran J Pharm Res. 2015 Spring;14(2):505-512. PMID: 25901158.
Dornetshuber-Fleiss R, Heilos D, Mohr T, et al. The naturally born fusariotoxin enniatin B and sorafenib exert synergistic activity against cervical cancer in vitro and in vivo. Biochem Pharmacol. 2015 Feb 1;93(3):318-331. PMID: 25557295.
美国LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供：癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。
美国LKT Labs 是1988年在美国成立的，为全球提供先端的药物研发试剂、试剂盒、委托合成，并为药物生产企业提供原料，最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。
官方网站： http://www.lktlabs.com
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