LKT/甲氧西汀/M1679/10毫克

价格
¥6340.00
货号:M1679-10mg
浏览量:127
品牌:LKT Labs
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商品描述
  • Description
  • ProductInfo
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Description

MethysticinisakavalactoneoriginallyfoundinPipermethysticum(kavaplant).Methysticinexhibitsneuroprotective,neuromodulatory,andantifungalactivities.Methysticinmayalsodisplayanti-inflammatorybenefit,inhibitingactivationofNF-κBinlungadenocarcinomatissue.MethysticinactivatesNrf2inneuronsandastroglia,protectingagainstamyloid-β(Aβ)-inducedneurotoxicity.ThiscompounddisplaysantimicrobialefficacyagainstspeciesofFusarium,Trichoderma,andColletotrichum.Additionally,methysticininhibitspeakamplitudeofvoltage-gatedNa+channelsinhippocampalneurons.

ProductInfo

CasNo.

495-85-2

Purity

≥98%

Formula

C15H14O5

FormulaWt.

274.27

ChemicalName

(6R)-6-[(1E)-2-(1,3-Benzodioxol-5-yl)ethenyl]-5,6-dihydro-4-methoxy-2H-pyran-2-one

IUPACName

(2R)-2-[(E)-2-(1,3-benzodioxol-5-yl)ethenyl]-4-methoxy-2,3-dihydropyran-6-one

Synonym

Kavahin;Kavatin

MeltingPoint

132-134°C

Solubility

Solubleinalcohol,etheroracetone.Practicallyinsolubleinwater.

Appearance

White/Off-WhiteCrystallinePowder

ShippingandStorage

StoreTemp

-20°C

ShipTemp

Ambient

Downloads

MSDS

M1679MSDSPDF

InfoSheet

M1679InfoSheetPDF

References

ShaikAA,HermansonDL,XingC.Identificationofmethysticinasapotentandnon-toxicNF-kappaBinhibitorfromkava,potentiallyresponsIBLeforkava"schemopreventiveactivity.BioorgMedChemLett.2009Oct1;19(19):5732-6.PMID:19716299.

WruckCJ,GötzME,HerdegenT,etal.Kavalactonesprotectneuralcellsagainstamyloidbetapeptide-inducedneurotoxicityviaextracellularsignal-regulatedkinase1/2-dependentnuclearfactorerythroid2-relatedfactor2activation.MolPharmacol.2008Jun;73(6):1785-95.PMID:18334601.

XuanTD,ElzaawelyAA,FukutaM,etal.HerbicidalandFungicidalActivitiesofLactonesinKava(Pipermethysticum).JAgricFoodChem.2006Feb8;54(3):720-5.PMID:16448174.

MaguraEI,KopanitsaMV,GleitzJ,etal.Kavaextractingredients,(+)-methysticinand(+/-)-kavaininhibitvoltage-operatedNa(+)-channelsinratCA1hippocampalneurons.Neuroscience.1997Nov;81(2):345-51.Erratumin:Neuroscience1998May;84(1):323.PMID:9300426.

美国LKT Labs 是一家专注于防癌抗癌特殊化学品研究和开发的公司。主要提供:癌症药物、药物发现试剂盒、天然产物、广泛的生命科学研究试剂、定制合成。 美国LKT Labs 是1988年在美国成立的,为全球提供先端的药物研发试剂、试剂盒、委托合成,并为药物生产企业提供原料,最近几年在农药、水产养殖业有很大程度的开发。在LKT Labs 可以找到在其他地方找不到的产品。 官方网站: http://www.lktlabs.com 备 货 期: 2-5周 分类浏览: 所有分类 瘦肉精 (13) 代理品牌 (8130)