Product ID U6860Cas No.Purity ≥95%

• Description
• Product Info
• Shipping and Storage
• Downloads
• References

Description

Urocortin III is an endogenous peptide ligand and member of the corticotropin-releasing factor (CRF) family; it binds and activates CRF type 2 receptors. Urocortin III is expressed primarily in brain regions such as the hypothalamus (specifically the pituitary gland), but is also present in heart, kidney (adrenal glands), and gastrointestinal tissues. Urocortin III modulates stress responses and exhibits anorexigenic, anxiogenic, anxiolytic, and positive inotropic effects across a wide variety of in vivo models.

Product Info

PurityFormulaFormula Wt.Appearance

≥95%

C186H312N52O52S2

4173.01

White to off white powder

Shipping and Storage

Store TempShip Temp

-20°C

Ambient

Downloads

Info Sheet

U6860 Info Sheet PDF

References

Bagosi Z, Csabafi K, Palotai M, et al. The interaction of Urocortin II and Urocortin III with amygdalar and hypothalamic cotricotropin-releasing factor (CRF)--reflections on the regulation of the hypothalamic-pituitary-adrenal (HPA) axis. Neuropeptides. 2013 Oct;47(5):333-8. PMID: 23932308.

Takahashi K, Totsune K, Murakami O, et al. Urocortins as cardiovascular peptides. Peptides. 2004 Oct;25(10):1723-31. PMID: 15476939.

Suda T, Kageyama K, Sakihara S, et al. Physiological roles of urocortins, human homologues of fish urotensin I, and their receptors. Peptides. 2004 Oct;25(10):1689-701. PMID: 15476936.

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