- Description
- Product Info
- Shipping and Storage
- Downloads
- References
Description
Erdosteine is a thiol derivative that is clinically used to treat bronchitis and chronic obstructive lung diseases; it exhibits mucolytic, antioxidative, and anti-inflammatory activities. In vitro, erdosteine inhibits H2O2-induced oxidative stress and DNA damage in vitro by scavenging ROS. Additionally, this compound decreases levels of leukotriene B4 (LTB4) and leukotriene E4 (LTE4) in clinical subjects with chronic obstructive pulmonary disease (COPD).
Product Info
| Cas No. | 84611-23-4 |
|---|---|
| Purity | ≥98% |
| Formula | C8H11NO4S2 |
| Formula Wt. | 249.31 |
| Chemical Name | [[2-Oxo-2-[(tetrahydro-2-oxo-3-thienyl)amino]ethyl]- thio]acetic acid |
| IUPAC Name | 2-[2-oxo-2-[(2-oxothiolan-3-yl)amino]ethyl]sulfanylacetic acid |
| Synonym | RV-144; Secresolv |
| Melting Point | 156-158°C |
| Solubility | Slightly soluble in water, methanol or ethanol. |
| Appearance | White Crystal Powder |
Shipping and Storage
| Store Temp | Ambient |
|---|---|
| Ship Temp | Ambient |
Downloads
| MSDS | E6814 MSDS PDF |
|---|---|
| Info Sheet | E6814 Info Sheet PDF |
References
Marabini L, Calò R, Braga PC. Protective effect of erdosteine metabolite I against hydrogen peroxide-induced oxidative DNA-damage in lung epithelial cells. Arzneimittelforschung. 2011;61(12):700-6. PMID: 22282957.
Dal Negro RW, Visconti M, Tognella S, et al. Erdosteine affects eicosanoid production in COPD. Int J Clin Pharmacol Ther. 2011 Jan;49(1):41-5. PMID: 21176724.
>>> 更多资讯详情请访问蚂蚁淘商城
