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ForimagingwiththeLeicaTCSSP8CARSconfocalmicroscope,specimendonothavetobestained.TheCoherentanti-StokesRamanScattering(CARS)technologyinvolvestwolaserbeamstovisualizethevibrationalcontrastofmoleculesinspecimens.Thespecimenremainsalmostunaffected.
TheuserprofitsofawiderangeoflivecellimagingwiththecombinationofvisIBLe,IRandUVlasers,secondharmonicgenerationandCARSsuchasanalyzinglivingcells,tissuesandevensmallwholeanimalsathighspeedorathighresolution.
Withitsflexibilityandconvenienthandling,theLeicaTCSSP8CARSistheidealdeviceforresearchinstitutesandmulti-userfacilities.

Imagingofnativespecimenwithoutdyes
Theintegrationofthelabel-freeCARStechnologyintotheLeicaTCSSP8confocalplatformovercomesthelimitationofdye-basedimagingmethods.Imagingofthecharacteristicintrinsicvibrationalcontrastofthepuremoleculesinthesampledoesnotrequireanystaining.Thismethodisnon-toxic,non-destructiveandminimallyinvasive.

MultispectralimagingwithVIS,UV,IR,SHGandCARS
TheLeicaTCSSP8CARSisaplatformprovidingvariousimagingmethodssuchasCARS,singlephotonormultiphotonfluorescenceorforimagingwithUVlasersinsimultaneousorsequentialmode.
Lasersources,scannermodelandimagingmodecanbeoptimallyadaptedtotheapplicationofinterestandsetupthroughthesystemsoftwareLeicaLASAF.Theergonomicandintuitivehandlingensuresthatambitiousexperimentsrunsmoothly.

Easyexperimentsetupwithafullyintegratedsystem
ThecompactCARSlaserisfullycontrolledthroughthesystemsoftwareLASAF.Thetightintegrationofthelasercontrolintothesoftwaremakesthesophisticatedprocessofadjustingmultipleparametersofthesystemcompletelytransparent.ThissolutionoffersthemostconvenientwaytoperformCARSexperiments–forexpertsandnovicesalike.
Videorateandhighresolutioninonesystem
LeicaTCSSP8CARSincludestheLeicaTandemScanner.Itcomprisesaconventionalscannerforallmorphologyandclassicalspeedlivecellapplicationsandaresonantscannerthatprovidesawiderangeofhighspeedoptions.ThiscombinationoftwoscannerscoversamultitudeofapplicationsandmakestheLeicaTCSSP8CARSaflexibledevicefittedformulti-userfacilities.


