OGR1/GPR68Catalogue number: X1601C

Product Type	Control Lysate
Units	100 µl
Species reactivity	Human
Application	Western Blotting

BackgroundOGR1 (originally identified as GPR68) is a high-affinity receptor for sphingosylphosphorylcholine (SPC).SPC is a member of a class of bioactive lipids which regulate cellular functions.These functions include cell proliferation and growth inhibition, smooth muscle contration and wound healing.SPC also stimulated signalling pathways that induce tyrosine phosphorylation, activate MAP kinases and protein kinase C, modify ion channel activity and increase intracellular Ca2+ concentration.OGR1 is expressed in placenta, lung, liver, spleen, testis, small intestine and peripheral blood leukocytes.It is not found in thymus, ovary, colon, skeletal muscle, kidney or pancreas.

Product

Product Form: Unconjugated

Formulation: Provided in 10% glycerol, 0.063 M Tris-HCl (pH 6.8), 2% SDS and 0.002% bromophenol blue, 5% 2-mercaptoethanol

Concentration: See vial for concentration

ApplicationsFor use as a positive control with Exalpha's OGR1 polyclonal antibody (Cat. No. X1600P) for Western blot analysis.

Functional Analysis: Western Blotting

StorageProduct should be stored at -20ºC. Aliquot to avoid freeze/thaw cycles

Product Stability: Products are stable for one year from purchase when stored properly

Shipping Conditions: Ship at ambient temperature, freeze upon arrival

CautionThis product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. It may contain hazardous ingredients. Please refer to the Safety Data Sheets (SDS) for additional information and proper handling procedures. Dispose product remainders according to local regulations.This datasheet is as accurate as reasonably achievable, but Nordic-MUbio​ accepts no liability for any inaccuracies or omissions in this information.

References1. Xu, Y., et al. 'Sphingosylphosphorylcholine is a ligand for ovarian cancer G-protein-coupled receptor 1.' Nature Cell Biol. 2000: 2, 261-267

Safety Datasheet(s) for this product:NM_Glycerol/wp-content/uploads/SDS/SDS Antibodies with glycerol Nordic-MUbio.pdf

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