HSD11B1 Antibody is a Rabbit Polyclonal against HSD11B1.

Target	HSD11B1
Clonality	Polyclonal
Reactivity	Human
Tested Applications	ELISA, IHC
Host	Rabbit
Recommended dilutions	IHC: 1/20 - 1/200. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	Recombinant human Corticosteroid 11-beta-dehydrogenase isozyme 1 protein (25-292AA).
Isotype	IgG
Form	Liquid
Purification	Antigen Affinity Chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P28845 (UniProt, ExPASy)
UniProt Secondary AC	B2R9Z1, D3DT89
UniProt Entry Name	DHI1_HUMAN
Gene Symbol	HSD11B1
GeneID	3290
OMIM	600713
KEGG	hsa:3290
String	9606.ENSP00000355995
Buffer	PBS, pH 7.3, containing 0.02% sodium azide and 50% glycerol.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on 11-Beta-Hydroxysteroid Dehydrogenase Type 1 (HSD11B1) Antibody RNA Interference Products RNA干扰（RNA interference, RNAi）是指在进化过程中高度保守的、由双链RNA（double-stranded RNA，dsRNA）诱发的、同源mRNA高效特异性降解的现象。基因沉默，主要有转录前水平的基因沉默(TGS)和转录后水平的基因沉默(PTGS)两类:TGS是指由于DNA修饰或染色体异染色质化等原因使基因不能正常转录;PTGS是启动了细胞质内靶mRNA序列特异性的降解机制。有时转基因会同时导致TGS和PTGS。 由于使用RNAi技术可以特异性剔除或关闭特定基因的表达，（长度超过三十的dsRNA会引起干扰素毒性）所以该技术已被广泛用于探索基因功能和传染性疾病及恶性肿瘤的治疗领域。