Rabbit polyclonal antibody to 14-3-3 eta.

Target	14-3-3 eta
Clonality	Polyclonal
Reactivity	Human, Mouse, Rat, Cow, Monkey
Tested Applications	WB, IHC, IF/ICC
Host	Rabbit
Recommended dilutions	WB: 1/500 - 1/1000, IHC: 1/100 - 1/200, IF/ICC: 1/100 - 1/500. Optimal dilutions/concentrations should be determined by the end user.
Immunogen	KLH-conjugated synthetic peptide encompassing a sequence within the center region of human 14-3-3 eta. The exact sequence is proprietary.
Isotype	IgG
Form	Liquid
Purification	The antibody was purified by immunogen affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	Q04917 (UniProt, ExPASy)
UniProt Entry Name	1433F_HUMAN
Gene Symbol	YWHAH
GeneID	75332262925576
KEGG	hsa:7533
String	9606.ENSP00000248975
Buffer	0.42% Potassium phosphate, 0.87% Sodium chloride, pH 7.3, 30% glycerol and 0.01% sodium azide.
Specificity	Recognizes endogenous levels of 14-3-3 eta protein.
Availability	Shipped within 5-10 working days.
Note	This product is for research use only.

Research Articles on 14-3-3 Eta (YWHAH) Antibody RNA Interference Products RNA干扰（RNA interference, RNAi）是指在进化过程中高度保守的、由双链RNA（double-stranded RNA，dsRNA）诱发的、同源mRNA高效特异性降解的现象。基因沉默，主要有转录前水平的基因沉默(TGS)和转录后水平的基因沉默(PTGS)两类:TGS是指由于DNA修饰或染色体异染色质化等原因使基因不能正常转录;PTGS是启动了细胞质内靶mRNA序列特异性的降解机制。有时转基因会同时导致TGS和PTGS。 由于使用RNAi技术可以特异性剔除或关闭特定基因的表达，（长度超过三十的dsRNA会引起干扰素毒性）所以该技术已被广泛用于探索基因功能和传染性疾病及恶性肿瘤的治疗领域。