11-Beta-Hydroxysteroid Dehydrogenase Type 2 Antibody is a Rabbit Polyclonal against 11-Beta-Hydroxysteroid Dehydrogenase Type 2.

Target	11-Beta-Hydroxysteroid Dehydrogenase Type 2 (HSD11b2)
Clonality	Polyclonal
Reactivity	Rat
Tested Applications	WB, IHC, IF/ICC, IP
Host	Rabbit
Recommended dilutions	WB: 0.2-2 µg/ml, IHC: 5-20 µg/ml, IF/ICC: 5-20 µg/ml. Optimal dilutions/concentrations should be determined by the end user.
Conjugation	Unconjugated
Immunogen	HSD11b2 (Leu58-Pro393)
Isotype	IgG
Form	Liquid
Purification	Purified by antigen-specific affinity chromatography, followed by Protein A affinity chromatography.
Storage	Aliquot and store at -20°C. Avoid repeated freeze/thaw cycles.
UniProt Primary AC	P50233 (UniProt, ExPASy)
UniProt Entry Name	DHI2_RAT
String	10116.ENSRNOP00000023130
Buffer	PBS, pH 7.4, containing 0.02% NaN3, 50% glycerol.
Specificity	The antibody is a rabbit polyclonal antibody raised against HSD11b2. It has been selected for its ability to recognize HSD11b2 in immunohistochemical staining and western blotting.
Availability	Shipped within 5-7 working days.
Note	This product is for research use only.

Research Articles on 11-Beta-Hydroxysteroid Dehydrogenase Type 2 (HSD11b2) Antibody RNA Interference Products RNA干扰（RNA interference, RNAi）是指在进化过程中高度保守的、由双链RNA（double-stranded RNA，dsRNA）诱发的、同源mRNA高效特异性降解的现象。基因沉默，主要有转录前水平的基因沉默(TGS)和转录后水平的基因沉默(PTGS)两类:TGS是指由于DNA修饰或染色体异染色质化等原因使基因不能正常转录;PTGS是启动了细胞质内靶mRNA序列特异性的降解机制。有时转基因会同时导致TGS和PTGS。 由于使用RNAi技术可以特异性剔除或关闭特定基因的表达，（长度超过三十的dsRNA会引起干扰素毒性）所以该技术已被广泛用于探索基因功能和传染性疾病及恶性肿瘤的治疗领域。