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The FOX family of transcription factors is a large group of proteins that share a common DNA binding domain termed a winged-helix or forkhead domain. FOXP3 is essential for normal immune homeostasis. It represses transcription through a DNA binding forkhead domain, thereby regulating T cell activation.
Titering of the FOXP3 antibody may be required for optimal performance.
1. The prediluted format is supplied in a dropper bottle and is optimized for use in IHC. After epitope retrieval step (if required), drip mAb solution onto the tissue section and incubate at RT for 30 min.
An N-terminal recombinant protein fragment was used as the immunogen for this FOXP3 antibody.
Store the FOXP3 antibody at 2-8oC (with azide) or aliquot and store at -20oC or colder (without azide).
Scurfin
