NSJ Bio/CD74 Antibody [clone CLIP/7193] (V4064)/100 ug/V4064-100UG

价格
¥9980.00
货号:V4064-100UG
浏览量:127
品牌:NSJ Bio
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商品描述
Description

It recognizes a protein of ~35kDa, identified as CD74 (Workshop IV). CD74 is a type II transmembrane protein which binds to the peptide binding groove of newly synthesized MHC class II alpha/beta heterodimers and prevents their premature association with endogenous polypeptides. CD74 is expressed primarily by antigen presenting cells, such as B-lymphocytes (from before the pre-B cell stage to before the plasma cell stage), macrophages, and monocytes, and many epithelial cells. Anti-CD74 stains predominantly germinal center lymphocytes and B-cell lymphomas, but rarely T-cell lymphomas. Anti-CD74 has been shown to be useful in differentiating atypical fibroxanthoma (-) from malignant fibrous histiocytoma (+).

Application Notes

Optimal dilution of the CD74 antibody should be determined by the researcher.

Immunogen

A recombinant fragment from the human protein was used as the immunogen for the CD74 antibody.

Storage

Aliquot the CD74 antibody and store frozen at -20oC or colder. Avoid repeated freeze-thaw cycles.

NSJBio F53723说明书   ABO Antibody [clone 593CT3.2.2] (F53723) F53723-0.1ML In ascites with 0.09% sodium azide 0.1 ml 299       可用性 1-3个工作日 物种反应性 人的 格式 腹水 克隆 单克隆(小鼠来源) 同型 小鼠IgM 克隆名称 593CT3.2.2 纯度 腹水 UniProt的 P16442 应用 蛋白质印迹:1:200-1:6400 限制 该ABO抗体仅供研究使用。   描述 该基因编码与发现的血型系统ABO相关的蛋白质。个体中存在哪个等位基因决定了血型。'O'血型由蛋白质N-末端附近的鸟嘌呤-258的缺失引起,其导致几乎完全不同的蛋白质的移码和翻译。具有A,B和AB等位基因的个体表达将H抗原转化为A或B抗原的糖基转移酶活性。已发现该基因的其他次要等位基因。 应用笔记 由于方案和二级/底物灵敏度的差异,可能需要滴定ABO抗体。 免疫原 来自人蛋白质的氨基酸41-68的一部分用作该ABO抗体的免疫原。 存储 将ABO抗体等分,并在-20℃或更低温度下冷冻保存。避免反复冻融循环。