Kim-1 is a type I trans-membrane structural glycoprotein located in the renal proximal tubule epithelial cells.  These cells undergo regeneration after various forms of injury and shed Kim-1 antigen into the urine.  Thus, urinary Kim-1 is an early and specific biomarker for tubular kidney injury.  Kim-1 has become widely recognized by many organizations and agencies, including the FDA, as an excellent biomarker in pre-clinical studies to monitor acute kidney tubular toxicity by identifying adverse reactive drugs and therapeutic agents in drug development.

Kidney injury caused by therapeutic agents and drug induction is a common type of injury requiring appropriate monitoring and intervention.  Current standards using blood urea nitrogen and creatinine are considered late indicators of kidney injury and are often non-specific.  Kim-1 has been shown continually to outperform traditional biomarkers of kidney injury in preclinical biomarker studies. The detection of Kim-1 can occur in as little as six hours post injection of an agent known to cause kidney injury.

The Rat Rena-strip test is a 15-minute qualitative (or quantitative with optional reader) lateral flow assay. Rat urine samples are added to the cassette and results can be read within 15 minutes.

Specifications:

Kit Contents:

• Rat Rena-strip cassettes in white foil pouches with dessicant, 25 cassettes

Storage Temperature: Store at room temperature.

Shipping Temperature: Ambient

Stability: 2 years from date of manufacture

Product is for research use only.

BioAssay Works-NakedGold®溶胶高度浓缩，可提供15 OD / mL。它们是使用不涉及传统沸腾和离心的方法生产的。它们“可结合”，因此无需浓缩即可将抗体或其他蛋白质包被在金上，从而节省了时间并减少了浪费。裸金溶胶具有出色的批间一致性。显示所有4结果默认排序默认排序按人气排序按平均评分排序按新旧程度排序按价格排序：从低到高按价格排序：从高到低价钱人气度评分显示20产品显示20产品显示40产品显示60产品裸金® 20纳米浓缩金溶胶$ 58.50 – $ 2,601.10选择选项裸金® 30纳米浓缩金溶胶$ 58.50 – $ 2,601.10选择选项裸金® 40nm的浓金溶胶- 15 OD /毫升$ 58.50 – $ 2,601.10选择选项裸金® 40nm的浓金溶胶- 50 OD / mL的$ 195.00 – $ 8,678.90