OVERVIEW:

Synonyms	Monoclonal Cytokeratin 7 antibody, Anti-Cytokeratin 7 antibody, Keratin K7 antibody, Cytokeratin -7, Cytokeratin 7, Cytokeratin 7, Cytokeratin -7 antibody, Cytokeratin 7 antibody
Specificity	Human cytokeratin 18
Cross Reactivity	Bovine, human, pig, sheep
Applications	IHC-F, WB
Immunogen	Cytokeratin 7 antibody was raised in mouse using cytoskeletal proteins from cultured HeLa cells as the immunogen.

SPECIFICATIONS:

Host	Mouse
Clone	Ks7.18
Isotype	IgG1
Method of Purification	Protein A affinity chromatography
Form & Buffer	Lyophilized from a solution containing 0.5% BSA and 0.09% NaN3. Reconstitute with 1ml of distilled water.

STORAGE & SAFETY:

Storage	Store at 4 deg C until reconstitution. Following reconstitution aliquot and freeze at -20 deg C for long term storage. Avoid repeated freeze-thaw cycles.
Biohazard Information	This product contains sodium azide as preservative. Although the amount of sodium azide is very small appropriate care must be taken when handling this product.

Usage Assay Information:

Usage Recommendations	IHC-F: 1:50

GENERAL INFORMATION:

Biological Significance

Cytokeratins are proteins of keratin-containing intermediate filaments found in the intracytoplasmic cytoskeleton of epithelial tissue. Cytokeratin represents an excellent marker for the discrimination of specific subtypes of adenocarcinoma. Keratin, type I cytoskeletal 7 also known as cytokeratin-7 (CK-7) or keratin-7 (K7) or sarcolectin (SCL) is a protein that in humans is encoded by the KRT7 gene. Keratin 7 is a type II keratin. It is specifically expressed in the simple epithelia lining the cavities of the internal organs and in the gland ducts and blood vessels.

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