OVERVIEW:

Synonyms	MonoclonalCD45antibody,Anti-CD45antibody,HCAMantibody,CD45,CD45antibody,CD-45antibody,CD-45,SCIDduetoPTPRCdeficiencyantibody,LCAantibody,Proteintyrosinephosphatasereceptortypecpolypeptideantibody,B220antibody,receptortypeantibody,T200glycoproteinantibody,proteintyrosinephosphataseantibody,LCAantibody,Leukocytecommonantigenantibody,Pgp1antibody,H-CAMantibody,CD45
Specificity	Human
CrossReactivity	Tobedeterminedbyend-user
Applications	Useroptimized
Immunogen	CD45antibodywasraisedinmouseusinghumanbloodlymphocytesastheimmunogen.

SPECIFICATIONS:

Host	Mouse
Clone	M504525
Isotype	IgG2a
MethodofPurification	CD45antibodywaspurifiedbychromatographyonproteinASepharose.
Form&Buffer	PurifiedfrommurineascitesbycolumnchromatographyandsuppliedinPBS,pH7.5,with0.08%NaN3.
Concentration	Batchdependent-pleaseinquireshouldyouhavespecificrequirements

STORAGE&SAFETY:

Storage	Storeat4degC.
BiohazardInformation	Thisproductcontainssodiumazideaspreservative.Althoughtheamountofsodiumazideisverysmallappropriatecaremustbetakenwhenhandlingthisproduct.

GENERALINFORMATION:

BIOLOGicalSignificance	TheCD45familyconsistsofmultiplemembersthatareallproductsofasinglecomplexgene.Thisgenecontains34exonsandthreeexonsoftheprimarytranscriptsarealternativelysplicedtogenerateuptoeightdifferentmaturemRNAsandaftertranslationeightdifferentproteinproducts.ThesethreeexonsgeneratetheRA,RBandRCisoforms.CD45isinvolvedintheco-stimulationofbloodcells.

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