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商品描述
DESCRIPTION:GLP, in complex with the highly homologous G9a, is the major histone H3 lysine-9 (H3K9) methyltransferase for euchromatin and can also dimethylate p53K373, a modification correlating with levels of inactive p53. This latter result, along with the fact that GLP and G9a are overexpressed in a variety of human cancers suggests G9a/GLP inhibition as a potential anti-cancer therapy, especially for tumors expressing wild-type p53.
Reaction Biology Corp.是一家专业从事早期药物发现研究的行业***和创新者。成立于2001年，Reaction Biology Corp.提供了广泛的服务，服务包括对激酶和后生生化和基于细胞的高通量筛选(HTS)和选择性复合分析的可靠的分析技术。Reaction Biology Corp.还提供相关的HTS实验试剂，包括高纯度和特化的表观遗传蛋白。每年有数百万的HTS和分析反应在我们的协助下完成。全球有超过750家公司，包括制药、生物技术、学术和非盈利性实验室，在使用Reaction Biology Corp.的生化和细胞分析服务并购买表观遗传蛋白。
ACCESSION #: NM_024757
Uniprot Link
INCLUDES AMINO ACIDS: 894-1298 (C-term.)
TAG(S): N-terminal GST-tag
MW: 80.0 kDa
EXPRESSION SYSTEM: E. coli
SUPPLIED AS: Solution of purified recombinant protein in 25.4 mM Na2HPO4/NaH2PO4, pH 7.4, 137 mM NaCl, 2.7 mM KCl, 3 mM DTT, 30% (w/v) glycerol.
STORAGE: -80°C, aliquot and snap-freeze after first use. first use.
View Product Data Sheet
Substantial Discounts Available on Bulk Quantities
We also offer assay services for GLP.
