- ZenBioInc
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- DNA extraction from freshfrozen and formalinfixed, paraffin...
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- ...fuels adipocyte differentiation and lipogenesis
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- ...formalinfixed paraffinembedded and freshfrozen samples
Zenbioisproudtoofferseveralnon-animalreplacementsforFetalBovineSerum(FBS):HumanPlateletLysate-(New!),GroProready-to-usegrowthsupplementandHumanABSerum.
ZenBio,Inc.IntroducesGroPro™CellCultureGrowthSupplement
FormulatedtoReplaceBovineSerumAllowingforCulturingof
PrimaryCellsandCellLines

OurNEW!HumanPlateletLysate(HPL)andGroProareanon-animalderivedcellculturegrowthsupplementsobtainedfromhumanplatelets.HPLcontainsabundantgrowthfactorsandcytokinesnecessaryforcellgrowthandproliferation.PlateletlysatecanbeusedasareplacementfortrADItionalFetalBovine(FBS)supplementedcellculturemedium.Replacingfetalbovineserum(FBS)withHPLallowsforexpansionandpotentialclinicalgradeproductionoffunctionalmesenchymalstromalcellsbyremovingtheriskofxenogeneicimmunereactionsandtransmissionofbovineprionandviralpathogens.Additionally,HPLandGroProarederivedfromarenewablesourcethatisnottiedtotheanimalslaughterindustryandthepricedoesnotfluctuate!
TheUSFDAismovingtowardsadoptingEuropeanguidelinesrequiringthatbovinematerialsberemovedfromculturingmediaforanytherapeuticproductcontainingculturedcells,thusmakingHPLanattractivealternativetotheR&Dandproduction/manufacturingprocesses.AlllotsarefullytestedforpathogensaccordingtoFDAguidelines.

- 10XmorepotentthanFBS
- StablePricing
- Non-AnimalDerived
- TraceABIlity
- FreeofMycoplasma
- Lot-to-LotConsistency
- SterileCollection
- PoolProcessing
- QCTestedinZenBio"sCellProductionSystem
HumanABSerum:
Humanserumoffersatechnicaladvantageoveranimalserumwhenculturingavarietyofhumancelltypes,especiallythosecellsmakinguptheimmunesystem.Thisisalsotheserumofchoicewhendevelopingtissueengineeredandregenerativemedicineproducts,asmanyregulatoryagenciesinagrowingnumberofcountriesarerestrictingtheuseofanimalserumduringthemanufacturingprocess.
SincehumanserumfromtypeABdonorsislackinginantibodiestowardstheAandBblood-typeantigens,thisisthetypemostcommonlyusedasimmunoreactivityisminimizedagainstthehumancellsinculture.Maledonorserumispreferredoverfemale,asthislowerstheriskofmajorhistocompatibilityclass(MHC)antibodiesbeingpresent.WomenhavingapastpregnancymayhavedevelopedtheseantibodiestoMHCantigenscarriedonthefather"scellsorthedevelopingfetus.
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