MammaryFibroblastCryopreservationMedium

Themajorityofbreastcancersoriginateinthelobularorductalcellsofthemilk-producingglands.Inthesestructures,therearetwomaincelltypes:theinnerluminalcellssurroundedbybasalmyoepithelium.Thesecellstypesaredistinctandaretheprecursorstovariousformsofbreastcancer.Assuch,itisimportanttostudythesecellpopulationsindependentlyaswellasinco-culturemodelssystems.Zenbioisproudtooffercryopreseveredhumanmammaryepithelialcells.

CellshavetestednegativeforHIV-1,HIV-2,HTLV-1,HTLV-2,HbsAG,HbcAB,HCV,andRPR.

Basalmyoepithelialcellsurroundtheluminalcellsandhavebothcontractilemuscleandepithelialproperties.Basalmyoepithelialcellstendtodominatenormalprimarycultures.Additionally,basal-typebreastcancersaretypicallyestrogenandprogesteronereceptornegative.

Luminalcellslinetheapicalsurfaceofthenormalbreastductandhavesecretoryproperties.MostbreastcancersarisefromluminalcellsandareheterogeneousintheirexpressionofhormonereceptorsandERBB2expression.

ZenBio提供了多种检测方法来检测作为潜在糖尿病或肥胖疗法的化合物。客户可以从以下任何一种检测方法中进行选择，或者我们可以设计一个针对每个客户的特定研究需求的定制程序。