Cat-Nr.	101-M113
Size	100 µg
Price	275 €
Category	Monoclonal Antibody
Clone Nr.	(#9G10)
Isotype	IgG2
Species Reactivity	Human
Formulation	lyophilized
Buffer	PBS
Reconstitution	Centrifuge vial prior to opening. Reconstitute the antibody with 500 µl sterile PBS and the final concentration is 200 µg/ml.
Stability and Storage	Lyophilized samples are stable for 2 years from date of receipt when stored at -20°C. Reconstituted antibody can be aliquoted and stored frozen at < -20°C for at least six months without detectable loss of activity.
Preparation	This antibody was produced from a hybridoma (mouse myeloma fused with spleen cells from a mouse immunized with purified human recombinant human MMP-10). The IgG2 fraction of the tissue culture supernatant was purified by Protein G affinity chromatography.
Antigen	recombinant human MMP-10
Application	WB, IHC (P)
Synonyms	MMP10; SL-2; STMY2
Description	Matrix metalloproteinases are a family of zinc and calcium dependent endopeptidases with the combined ability to degrade all the components of the extracellular matrix. MMP10 (stromelysin 2) degrades a broad range of substrates including gelatin, collagen types III, IV and V, fibronectin, aggrecan, and pig cartilage proteoglycan. MMP10 can activate other MMPs such as MMP1 and MMP8. MMP10 is expressed in keratinocytes, T cells, menstrual endometrium and a few tumor samples. Structurally, MMP10 may be divided into four distinct domains: a prodomain which is cleaved upon activation, a catalytic domain containing the zinc binding site; a short linker region, and a carboxyl terminal hemopexin- slike domain.
Uniprot ID	P09238
Protein RefSeq	NP_002416.1
mRNA RefSeq	NM_002425.2

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