Cat-Nr.	M10-026
Size	10 µg
Price	170 €
Source	E. coli
Formulation	lyophilized
Purity Confirmation	> 98% by SDS-PAGE & HPLC analyses
Length [aa]	125
Molecular Weight	13.8 kDa
Endotoxin Levels	< 0.1 ng/µg of protein (<1EU/µg)
Biological Activity	Determined by its ability to chemoattract Balb/C mouse spleen MNCs using a concentration range of 1.0-20.0 ng/ml.
Species Reactivity	Human, Mouse, Rabbit, Monkey, Bacteria
Synonyms	Ccl2; JE; HC11; MCAF; MCP1; MCP-1; Scya2; Sigje; SMC-CF; AI323594
Description	The MCP proteins belong to the CC chemokine family, and signal through CCR2 and, with the exception of MCP-1, other CCR receptors. The MCP proteins chemoattract and activate monocytes, activated T cells, basophils, NK cells, and immature dendritic cells. The MCP family cross reacts across species. Recombinant murine JE is a 13.8 kDa protein containing 125 amino acid residues including the four highly conserved cysteine residues present in the CC chemokines.
Protein Sequence	QPDAVNAPLT CCYSFTSKMI PMSRLESYKR ITSSRCPKEA VVFVTKLKRE VCADPKKEWV QTYIKNLDRN QMRSEPTTLF KTASALRSSA PLNVKLTRKS EANASTTFST TTSSTSVGVT SVTVN
Uniprot ID	P10148
Protein RefSeq	NP_035463.1
mRNA RefSeq	NM_011333.3

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