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CatalogNo.:56506

Size:50ugpurifiedbyantigenaffinitychromatographyinPBScontaining0.02%sodiumazide.

TLR6isa796aaproteincontaining20N-terminalleucine-richrepeatmotifs(LRRs)withamolecularweightof91kDa.TLR6ismostcloselyrelatedtoTLR1,TLR10,andTLR2with68%,46%,and31%overallaasequenceidentity,respectively.Invivo,TLR6transcriptisobservedinthymus,spleen,andlung.TLR6mRNAexpressionishighestinBcellsandmonocytes.TLR6formsaheterodimerwithTLR2.LikeTLR1,TLR6isthoughttospecifyorenhanceTLR2andcontributetoitssignalingcapABIlitiesthroughheterodimerization.

Antigen:Syntheticpeptidecorrespondingto13aminoacidsnearthecenterofhumanTLR6.

HostSpecies:Rabbit

AntibodyClass:Polyclonal

Preservatives:0.02%sodiumazide

ThisantibodyrecognizeshumanTLR6.

Forinvitroinvestigationaluseonly.Notfor

useintherapeuticordiagnosticprocedures.

Westernblotting:useat0.5-1ug/ml.Abandofapproximately91kDaisdetected.

Immunohistochemistry:formalin-fixed,paraffin-embeddedtissues,useat5ug/ml.

Thymus:Formalin-fixedparaffin-embedded

Lungalveolarmacrophages:Formalin-fixedparaffin-embedded.

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.

Storeat4oC(short-term)or-70oC(long-term).

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