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蚂蚁淘在线 / 品牌中心 / QED Bioscience / QED生物科学/CD74/56451/1 Ea

QED生物科学/CD74/56451/1 Ea

价格
￥6500.00
货号：56451
浏览量：127
品牌：QED Bioscience
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productdatasheet


Anti-CD74MonoclonalAntibody


ORDERINGINFORMATIONCatalogNo.:56451(clonePIN1)Size:100uginPBS,pH7.4,purifiedbyProteinGaffinitychromatography.


BACKGROUND

CD74isanon-polymorphictypeIIintegralmembraneprotein.IthasashortN-terminalcytoplasmictailof28aminoacidsfollowedbyasingle24-aatransmembraneregionandanapproximately150-aalumenaldomain.CD74functionsmainlyasanMHCclassIIchaperonewhichpromotesERexitofMHCclassIImoleculesbydirectingthemtoendocyticcompartments,preventingpeptidebindingintheER,andcontributingtopeptide“editing”intheMHCclassIIcompartment.CD74hasrecentlybeenshowntohavearoleasanaccessorysignalingmoleculebecauseofitshigh-affinitybindingtothepro-inflammatorycytokinemacrophagemigrationinhibitoryfactor(MIF).


SPECIFICATIONSUMMARYAntigen:SyntheticpeptidecorrespondingtothehumanCD74invariantchain(aa12-

28)conjugatedtoKLH.HostSpecies:MouseAntibodyClass:IgG1

Preservatives:0.09%sodiumazideOtheradditives:50%glycerolSPECIFICITY

ThisantibodyrecognizeshumanCD74.


APPLICATIONS

Immunoblotting:useat1ug/ml.Adoubletbandof~33-35kDaisdetected.

Immunoprecipitation:useat12ug/ml.Immunocytochemistry:workingconcentrationissampledependent.Flowcytometry:workingconcentrationissampledependent.

Thesearerecommendedconcentrations.Usershoulddetermineoptimalconcentrationsfortheirapplication.

Positivecontrol:PALAcelllysate.


DILUTIONINSTRUCTIONS

DiluteinPBSormediumwhichisidenticaltothatusedintheassaysystem.


STORAGEANDSTABILITY

Thisantibodyisstableforatleastone(1)yearat-20oC.Avoidrepeatedfreezingandthawing.


Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.



QEDBioscience,Inc.10919TechnologyPlace,SuiteC

SanDiego,CA92127


TollFree800.929.2114

Phone858.675.2405

Fax858.592.1509

info@qedbio.com


Visitourwebsiteforadditionalproductinformationandtoorderonline.

qedbio.com

QED生物科技为科研客户提供优质的单克隆和多克隆抗体产品。 是一家提供全面服务的并提供额外服务的公司。能提供超过1500的单克隆和多克隆抗体的用于多领域的研究。