QED生物科学/重组人SERPINH1(Hsp47)/11125P-1000/1 Ea

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¥46000.00
货号:11125P-1000
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品牌:QED Bioscience
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RecombinantHumanSERPINH1(Hsp47)



ORDERINGINFORMATION


Formulation:Sterile-filteredcolorlesssolution(1mg/ml)in20mMTris-HCl,pH8.0,and10%glycerol.Purifiedbyproprietarychromatographictechniques.


BACKGROUND

SERPINH1isamemberoftheserpinsuperfamilyofserineproteinaseinhibitorswhoseexpressionisinducedbyheatshock.Asamolecularchaperone,itlocalizestotheendoplasmicreticulumlumenandbindscollagen,thusparticipatinginthematurationofcollagenmolecules,facilitatingthefoldingandassemblyofprocollagenmolecules,retainingunfoldedmoleculeswithintheER,andassistinginthetransportofcorrectlyfoldedmoleculesfromtheERtotheGolgiapparatus.AutoantibodiestoSERPINH1havebeenfoundincasesofrheumatoidarthritis.


DESCRIPTION

RecombinanthumanSERPINH1producedinE.coliisasingle,non-glycosylatedpolypeptidecontaining439aminoacids(aa18-417)withamolecularweightof48.9kDa.Itisfusedtoa37-aminoacidHis-tagattheN-terminus.


SPECIFICATIONSUMMARY

CatalogNumber

Size

11125P-10

10ug

11125P-50

50ug

11125P-1000

1000ug

CatalogNumber

Size

11125P-10

10ug

11125P-50

50ug

11125P-1000

1000ug

Source:EscherichiacoliPurity:Greaterthan90%asdeterminedbySDS-PAGE.Accessionnumber:P50454Aminoacidsequence:

RGSHHHHHHGMASMTGGQQMGRDLYDDDDKDRWGSHMAAEVKKPAAAAAPGTAEKLSPKAATLAERSAGLAFSLYQAMAKDQAVENILVSPVVVASSLGLVSLGGKATTASQAKAVLSAEQLRDEEVHAGLGELLRSLSNSTARNVTWKLGSRLYGPSSVSFADDFVRSSKQHYNCEHSKINFRDKRSALQSINEWAAQTTDGKLPEVTKDVERTDGALLVNAMFFKPHWDEKFHHKMVDNRGFMVTRSYTVGVMMMHRTGLYNYYDDEKEKLQIVEMPLAHKLSSLIILMPHHVEPLERLEKLLTKEQLKIWMGKMQKKAVAISLPKGVVEVTHDLQKHLAGLGLTEAIDKNKADLSRMSGKKDLYLASVFHATAFELDTDGNPFDQDIYGREELRSPKLFYADHPFIFLVRDTQSGSLLFIGRLVRPKGDKMRDEL.


STORAGEANDSTABILITY

Storeat4oCifentirevialwillbeusedwithin2-4weeks.Storeatorbelow-20oCforlongerperiodsoftime.Additionofacarrierprotein(suchas0.1%HSAorBSA)isrecommendedforlong-termstorage.


Forinvitroinvestigationaluseonly.Notforuseintherapeuticordiagnosticprocedures.


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