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蚂蚁淘在线 / 品牌中心 / QED Bioscience / QED Bioscience/Recombinant Human Mn Superoxide Dismutase (SOD2)/13003P-1000/1 Ea

QED Bioscience/Recombinant Human Mn Superoxide Dismutase (SOD2)/13003P-1000/1 Ea

价格
￥60000.00
货号：13003P-1000
浏览量：127
品牌：QED Bioscience
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商品描述


RecombinantHumanMnSuperoxideDismutase(SOD2)


ORDERINGINFORMATION

Catalognos.:13003P-55ug13003P-2525ug13003P-10001000ugFormulation:Sterile-filteredsolutionin20mMTris-HCl,pH8.0,20%glycerol.Purifiedbystandardchromatographictechniques.


BACKGROUND

SOD2ispartoftheiron/manganesesuperoxidedismutasefamily.Itencodesamitochondrialproteinthatformsahomotetramerandbindsonemanganeseionpersubunit.SOD2bindstothesuperoxidebyproductsofoxidativephosphorylationandconvertsthemtohydrogenperoxideanddiatomicoxygen.MutationsinSOD2genehavebeenassociatedwithidiopathiccardiomyopathy(IDC),prematureaging,sporADIcmotorneurondisease,andcancer.SOD2destroysradicalswhichareusuallyproducedwithinthecellsandwhicharetoxictoBIOLOGicalsystems.


DESCRIPTION

RecombinantHumanMnSOD2producedinE.coliisasingle,non-glycosylatedpolypeptidechaincontaining219aminoacids(aa25-222)withamolecularweightof24.4kDa.IthasaHis-tagattheN-terminus.


SPECIFICATIONSUMMARY

Source:EscherichiacoliPurity:Greaterthan95%asdeterminedbySDS-PAGE.Accessionnumber:P04179.2Aminoacidsequence:

MGSSHHHHHHSSGLVPRGSHMKHSLPDLPYDYGALEPHINAQIMQLHHSKHHAAYVNNLNVTEEKYQEALAKGDVTAQIALQPALKFNGGGHINHSIFWTNLSPNGGGEPKGELLEAIKRDFGSFDKFKEKLTAASVGVQGSGWGWLGFNKERGHLQIAACPNQDPLQGTTGLIPLLGIDVWEHAYYLQYKNVRPDYLKAIWNVINWENVTERYMACKK.


BIOLOGICALACTIVITY

Specificactivityis>1,200units/mginwhichoneunitwillinhibittherateofreductionofcytochromecby50%inacoupledsystemusingxanthineandxanthineoxidaseatpH7.8at25oCina1.5mlreactionvolume.


STORAGEANDSTABILITY

Storeat4oCifentirevialwillbeusedwithin2-4weeks.Storeat-20oCforlongerperiodsoftime.Additionofacarrierprotein(0.1%HSAorBSA)isrecommendedforlong-termstorage.Avoidmultiplefreeze-thawcycles.


Forinvitroinvestigationaluseonly.Notintendedforuseintherapeuticordiagnosticprocedures.

QED生物科技为科研客户提供优质的单克隆和多克隆抗体产品。 是一家提供全面服务的并提供额外服务的公司。能提供超过1500的单克隆和多克隆抗体的用于多领域的研究。