QED Bioscience/重组人Cu/Zn超氧化物歧化酶同型二聚体/13002P-100/1 Ea

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¥5340.00
货号:13002P-100
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品牌:QED Bioscience
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RecombinantHumanCu/ZnSuperoxideDismutase(SOD1)Homodimer


ORDERINGINFORMATION

Catalognos.:13002P-2020ug13002P-100100ug13002P-10001000ugFormulation:Lyophilizedfromasterile-filteredsolution(1mg/ml)inPBS,pH7.4Purifiedbyproprietarychromatographictechniques.


BACKGROUND

Cu/ZnSuperoxideDismutase(SOD1)catalyzesthereactionbetweensuperoxideanionsandhydrogentoyieldmolecularoxygenandhydrogenperoxide.Itprotectsacellfromdangerouslevelsofsuperoxide.SOD1bindscopperandzincionsandisoneofthreeisozymesresponsIBLefordestroyingfreesuperoxiderADIcals.MutationsinSOD1causeaformoffamilialamyotrophiclateralsclerosis(ALS).


DESCRIPTION

RecombinantHumanCu/ZnSOD1producedinE.coliisahomodimernon-glycosylatedpolypeptidechaincontaining2x154aminoacidswithamolecularweightof31.6kDa.


SPECIFICATIONSUMMARY

Source:EscherichiacoliPurity:Greaterthan95%asdeterminedbySDS-PAGEandRP-HPLC.Accessionnumber:P00441.2Aminoacidsequence:

MATKAVCVLKGDGPVQGIINFEQKESNGPVKVWGSIKGLTEGLHGFHVHEFGDNTAGCTSAGPHFNPLSRKHGGPKDEERHVGDLGNVTADKDGVADVSIEDSVISLSGDHCIIGRTLVVHEKADDLGKGGNEESTKTGNAGSRLACGVIGIAQ


SOLUBILITY

ReconstitutelyophilizedproductinsteriledistilledH2Otonolessthan100ug/mlwhichcanbefurtherdilutedinotheraqueoussolutionsasneeded.


BIOLOGICALACTIVITY

Potencypermgis10,000units/mgasdeterminedbythePyrogallicAcidmethod.


STORAGEANDSTABILITY

Althoughlyophilizedproductisstableatroomtemperaturefor3weeks,itisbeststoredatorbelow-20oC.Afterreconstitution,productshouldbestoredatorbelow-20oC.Additionofacarrierprotein(0.1%HSAorBSA)isrecommendedforlong-termstorage.


Forinvitroinvestigationaluseonly.Notintendedforuseintherapeuticordiagnosticprocedures.

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