QED Bioscience蚂蚁淘在线

Neutrophilelastaseisamajorneutralproteasepresentinhumanneutrophilsandisreleasedbyneutrophilsfollowingstimulationwithavarietyofstimuli.Itisbelievedtobeamajormediatorofthelungdestructionseeninemphysema.Inadditiontoelastin,neutrophilelastasecancleaveotherBIOLOGicallyactiveproteinssuchasfibrinogenandantithrombinandisreleasedbyneutrophilsduringclotformation.

SPECIFICATIONSUMMARY

Antigen:Purifiedhumanneutrophilelastase.

HostSpecies:Mouse

Specificity:TheseantibodiesrecognizehumanneutrophilelastaseandvaryintheirABIlitytoinhibitneutrophilelastaseactivityasdeterminedinanassayofelastase-mediatedhydrolysisofelastin-CongoRedsubstrate:

CatalogNo. 13201	%ElastaseInhibition 1.2
13202	4.1
13203	90.0
13204	82.0

APPLICATIONS

TheseantibodieshavebeenqualifiedforuseinELISAtodetecthumanneutrophilelastaseandinstudiesofinhibitionandenzymekineticsofhumanneutrophilelastase.

DILUTIONINSTRUCTIONS

DiluteinPBSormediumthatisidenticaltothatusedintheassaysystem.

STORAGEANDSTABILITY

Theseantibodiesarestableforatleastone(1)yearat-20oCto-70oC.Storeproductinappropriatealiquotstoavoidmultiplefreeze-thawcycles.

Forinvitroinvestigationaluseonly.Notintendedforuseintherapeuticordiagnosticprocedures.

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