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蚂蚁淘在线 / 品牌中心 / QED Bioscience / QED生物科学/CENP-A/12597/1 Ea

QED生物科学/CENP-A/12597/1 Ea

价格
￥6080.00
货号：12597
浏览量：127
品牌：QED Bioscience
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商品描述


CENP-AMonoclonalAntibody


ORDERINGINFORMATION

CatalogNo.:12597(clone5A7-2E11)Format:100uginPBS(1mg/ml),pH7.4,50%glycerol,0.09%sodiumazide.PurifiedbyProteinGaffinitychromatography.

BACKGROUND

Replicatedchromosomesincludetwokinetochoresthatcontrolchromosomesegregationduringmitosis.CentromereProtein-A(CENP-A),ahistoneH3-likeprotein,containsaC-terminalH3-likedomainwhichisrequiredforcentromerelocalizationofCENP-A.ItisessentialforkinetochoretargetingofCENP-C.InthepresenceofDNA,CENP-AformsanoctamericcomplexwithhistonesH2A,H2B,andH4.CENP-Aspecificallylocalizestoactivecentromeresandisacomponentofspecializedcentromericnucleosomesonwhichkinetochoresareassembled.

CENP-AisessentialfornucleosomalpackagingofcentromericDNAatinterphaseandfunctionsasacentromereformationMarkeronchromosomes.

SPECIFICATIONSUMMARY

Antigen:SyntheticpeptidecorrespondingtoasequencewithinhumanCENP-A.Accessionno.:P49450,NP_001035891.1HostSpecies:MouseAntibodyClass:IgG1Specificity:ThisantibodyrecognizeshumanCENP-A.Reactivitywithotherspecieshasnotbeeninvestigated.

APPLICATIONS

Immunoblotting:useat1ug/ml.Abandof

~18kDaisdetected.

DetectionofCENP-AinlysateofU2OScells


ELISA:useat1-10ug/mlwithCENP-Aonthesolidphase.

Positivecontrol:U2OScelllysate

Thesearerecommendedconcentrations;endusershoulddetermineoptimalconcentrationsfortheirapplications.

DILUTIONINSTRUCTIONS

DiluteinPBSormediumthatisidenticaltothatusedintheassaysystem.

STORAGEANDSTABILITY

Thisantibodyisstableforatleastone(1)yearat-20oC.Avoidrepeatedfreeze-thawcycles.

Forinvitroinvestigationaluseonly.Notintendedfordiagnosticortherapeuticapplications.

QED生物科技为科研客户提供优质的单克隆和多克隆抗体产品。 是一家提供全面服务的并提供额外服务的公司。能提供超过1500的单克隆和多克隆抗体的用于多领域的研究。