MD生物制品/完整PTH ELISA/96孔/M046016

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货号:M046016
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品牌:MD Bioproducts
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PTH (Parathyroid hormone, Parathormone, Parathyrin) is biosynthesized in the parathyroid gland as a pre-proparathyroid hormone, a larger molecular precursor consisting of 115 amino acids. Following sequential intracellular cleavage of a 25-amino acid sequence, preproparathyroid hormone is converted to an intermediate, a 90-amino acid polypetide, proparathyroid hormone. With additional proteolytic modification, proparathyroid hormone is then converted to parathyroid hormone, an 84 amino acid polypeptide. In healthy individuals, regulation of parathyroid hormone secretion normally occurs via a negative feedback action of serum calcium on the parathyroid glands. Intact PTH is biologically active and clears very rapidly from the circulation with a half-life of less than four minutes. PTH undergoes proteolysis in the parathyroid glands, but mostly peripherally, particularly in the liver but also in the kidneys and bone, to give N-terminal fragments and longer lived C-terminal and midregion fragments. In subjects with renal insufficiency, C-terminal and midregion PTH assays typically give elevated PTH results, as reflected by impaired renal clearance.

MD Bioproducts的ELISA法目录编号名称数量/尺寸M036005N小鼠OVA-IgE ELISA96口井M046006酶联免疫吸附测定96口井M046008Aggrecanase活性ELISA96口井M046009Aggrecanase活性,灵敏的ELISA96口井M046010降钙素ELISA96口井M056011内啡肽(β-Endorphin)ELISA96口井M046013EPO ELISA96口井M046043HtrA丝氨酸肽酶-1(HtrA1)ELISA,人类96口井M056014亮氨酸-脑啡肽酶联免疫吸附测定96口井M046015MMP-13(活化)ELISA96口井M046016PTH,完整ELISA96口井M056018P物质ELISA96口井