MD生物制品/Lumican,抗体/1042007/100微克

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面议
货号:1042007
浏览量:127
品牌:MD Bioproducts
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商品描述
Overview: 

Lumican(LUM)isthemajorkeratansulfateproteoglycanofthecorneaanditbindscollagenfibrils.Innoncornealtissues,lumicanispresentasalowornonsulfatedglycoproteinandhasbeenfoundintheaorta,cartilage,liver,skeletalmuscle,kidney,pancreas,brain,placentaandlung.Complicationsofthecorneahavebeenconfirmedusinglumican-nullmice.Thesemiceexhibitcornealopacity,skinfragility,andimpairedcollagenfibrillogenesis.Morerecentstudiesshowlumicanhasanintegralroleincellmigration,adhesionandproliferation.Theexpressionoflumicanhasalsobeenexaminedinbreast,pancreaticandcolorectalcancer.Theaffectoflumicandependsonthetypeofcancerasithasbeenshowntohavebothapositiveandnegativeaffectontumorgrowth.


RelatedTerms/Symbols

  • LUM
  • LDC
  • SLRR2D
  • P51884
  • Lumicanproteoglycan
  • majorkeratansulfateproteoglycan

 

 

Data/Specifications: 

 

Clone:Lum-1

 

Host:Mouse

 

Isotype:IgM

 

Purity:Affinitypurifiedonthiophiliccolumn

 

Form:Liquid,1mL/vial

 

Concentration:0.1mg/mL

 

Storage: -20°C.

 

Specificity:ThisLumicanantibodyrecognisesaproteinepitopeinlumicanderivedfromhuman,bovine,porcine&mousetissues.

How_To_Use:

 

Applications

 

  • WesternBlot:recommendeddilution0.2mg/mL
  • IHC

 

 

TechnicalNotes

ThisepitopeisbestrecognizedafterkeratanaseandkeratanaseIItreatment/digestion

ofsection(IHC)ortissueextracts(forWesternanalyses).InsomeIHCtissueanalyses,

chondroitinasetreatmentmayalsobeused,asthissecondenzymetreatmentfacilitates

antibodypenetrationintothetissue.

MD Bioproducts的ELISA法目录编号名称数量/尺寸M036005N小鼠OVA-IgE ELISA96口井M046006酶联免疫吸附测定96口井M046008Aggrecanase活性ELISA96口井M046009Aggrecanase活性,灵敏的ELISA96口井M046010降钙素ELISA96口井M056011内啡肽(β-Endorphin)ELISA96口井M046013EPO ELISA96口井M046043HtrA丝氨酸肽酶-1(HtrA1)ELISA,人类96口井M056014亮氨酸-脑啡肽酶联免疫吸附测定96口井M046015MMP-13(活化)ELISA96口井M046016PTH,完整ELISA96口井M056018P物质ELISA96口井