Specifications

One of the most potent and selective proteasome inhibitors, Epoxomycin inhibits all three activities of the proteasome. Epoxomicin (100 nM) results in a 30-fold increase in the levels of p53 protein, a known target of the proteasome, in HUVECs. Epoxomicin (10 μM) results in the accumulation of ubiquitinated proteins in HeLa cells. Epoxomicin (10 μM) inhibits IκBα degradation by 10-fold in HeLa cells.

Info

Purity	>99.0% by HPLC
Quantity	100 mg
Molecular Weight	554.72 Da
Physical State	Lyophilized powder
Solubility	DMSO (10 mg/mL)
CAS No.	134381-21-8
Storage	4°C, (-20°C Long term). The product can be shipped at room temperature.

Lifesensors 是一家生物技术公司，致力于为治疗，药物发现和研究市场开发支持技术。通过提供创新的研究工具，确立了在泛素和类泛素蛋白途径中的先进地位。此外，我们的原核和真核蛋白表达平台 SUMOpro 和 SUMOstar 在世界范围内被学术、政府、制药和生物技术实体所使用