Specifications

Ubiquitin is a small polypeptide that can be conjugated via its C-terminus to the primary amine groups of a lysine residue on target proteins. This covalent attachment is referred to as monoubiquitylation. Additional ubiquitin moieties can subsequently be conjugated to this initial ubiquitin, utilizing any one (of seven) lysine residue on the surface of ubiquitin. The formation of these ubiquitin chains is referred to as polyubiquitylation.

LifeSensors has produced a complete panel of tag-free recombinant human ubiquitins that are engineered to have all available lysines mutated to arginines except at position mentioned. For example, ubiquitin-K6 has all available lysines mutated to arginines except at position 6, such that this molecule can only form polyubiquitin chains of K6-linkage type. The panel consists of 1 mg of each Ub mutant- K6, K11, K27, K29, K33, K48, and K63. The panel also contains 1 mg each of wt Ub and ubiquitin-K0 (all lysines mutated to arginines).

Info

Contents	1 mg amounts of each of the following ubiquitins: wild-type, K0, K6, K11, K27, K29, K33, K48, and K63
Purity	>=95% (SDS-PAGE)
Physical State	Liquid in PBS pH 7.4
Storage	-80°C.  Avoid repeated freeze/thaw cycles

Lifesensors 是一家生物技术公司，致力于为治疗，药物发现和研究市场开发支持技术。通过提供创新的研究工具，确立了在泛素和类泛素蛋白途径中的先进地位。此外，我们的原核和真核蛋白表达平台 SUMOpro 和 SUMOstar 在世界范围内被学术、政府、制药和生物技术实体所使用