LifeSensors/UB308-25µg Cbl-b 25µg, E3 Ligase Enzyme/UB-0308-0025

价格
¥6900.00
货号:UB-0308-0025
浏览量:127
品牌:Life Sensors
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商品描述

Specifications

Cbl-bisanE3ligasewhichregulatesalargenumberofdifferentsignalingmoleculesinthecell.ThemammalianCblfamilyofproteinsishighlyconservedhroughoutevolutionfromnematodestohumansandconsistsofc-Cbl,Cbl-b,andCbl-3.AllthreemembersoftheCblfamilyofproteinsshareahighlyHomologoustyrosinekinase-binding(TKB)domain.TheTKBdomainisfollowedbyahighlyconservedhelicallinker(L)domainandaRING(reallyinterestingnewgene)finger(RF)domain,whichbindtoubiquitin-conjugatingenzymes(E2).Incontrast,theC-terminalregionsofthisfamilyofproteinsarelessconserved.Cbl-bhasbeendemonstratedtoplayacrucialroleinestablishingthethresholdforT-cellactivationandcontrollingperipheralT-celltoleranceviamultiplemechanisms.

Info

Purity> 95%bySDS-PAGE
MolecularWeight48kDa
Quantity25 mg
PhysicalStateLiquid
SourceHumanRecombinant
TagHis6+HA
StorageStoreat-80°C,avoidingrepeatedfreeze-thawcycles.
Lifesensors 是一家生物技术公司,致力于为治疗,药物发现和研究市场开发支持技术。通过提供创新的研究工具,确立了在泛素和类泛素蛋白途径中的先进地位。此外,我们的原核和真核蛋白表达平台 SUMOpro 和 SUMOstar 在世界范围内被学术、政府、制药和生物技术实体所使用