Specifications

Alvespimycin (17-DMAG) is a potent HSP90 inhibitor with IC₅₀ of 62 nM in a cell-free assay. Geldanamycin analog that displays superior pharmacological properties and induces apoptosis in a variety of tumor cell lines. Inhibits angiogenesis. Cell permeable.

Product Information

Purity:                           >98% by TLCMW:                                653.2Formula:                        C32H48N4O8.HClPhysical State:               Lyophilized purple powderAmount:                        1mg or 5mgSolubility:                      30 mg/ml in DMSO; 10 mg/mL in ethanolStorage:                         Store as supplied at -20°C for up to 2 years. Store solutions at -20°C for up to 3 months.

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