Specifications

Background

Selective inhibitor of aspartyl proteases1. Inhibits human pepsin, human gastricsin, renin, cathepsin D and E and bovine chymosin2. Does not inhibit thiol proteases, neutral proteases or serine proteases3. It suppresses RANKL-induced osteoclast differentiation4.

Product Information

Purity:                                       >98% by HPLCMW:                                           685.9Formula:                                   C34H63N5O9CAS No.                                     26305-03-3Physical State:                          Lyophilized white powderAmount:                                    5mg, 25mgSolubility:                                 5 mg/mL in DMSO; 1 mg/mL in ethanolStorage:                                    Store desiccated as supplied at -20°C for up to 2 years. Store solutions at -20°C for up to 2 months.

References

1. Merck Index 14:71472. J. Marciniszyn et al. J. Biol. Chem. 1976 251:70883. K Oda J. Biochem. 2012 151:134. H Yoshida et al. J. Biochem. 2006 139:583

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