生命传感器/UBE2D2(UbcH5b、E2-17K2)/UB-207H-0008

价格
¥900.00
货号:UB-207H-0008
浏览量:127
品牌:Life Sensors
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商品描述

Specifications

UBE2D2(alsoknownasE2-17K2)isanE2conjugationenzymethatisinvolvedintheubiquitylationoftargetsubstrates,alongwithE1andE3enzymes.TheUbcH5family(includingUbcH5aandUbcH5c,88%and89%sequenceidentitywithUbcH5b,respectively)arethehumanhomologuesoftheSacchromycescerevisiaeUBC4/5family(~79%sequenceidentity).MembersoftheUbcH5familyhavebeenimplicatedinanumberofinflammatoryandcancerpathways,includingtheubiquitylationofp53(involvingtheE3ligaseHdm2)andIκBα(involvingtheE3ligaseSCF).

Info

Amount0.8nmol
StateLiquid
MolecularWeight17,729.3Da
SourceHumanRecombinant
FusionTagHis6
AccessionNumberP62837
AlternateNamesE2-17K2,UbcH5b
Storage-80°C,avoidfreeze/thawcycles
StABIlity1yearunderrecommendedstorageconditions
RecommendedUseEnzymeconcentrationof100nM–1mMisrecommendedforinvitroconjugation.
Lifesensors 是一家生物技术公司,致力于为治疗,药物发现和研究市场开发支持技术。通过提供创新的研究工具,确立了在泛素和类泛素蛋白途径中的先进地位。此外,我们的原核和真核蛋白表达平台 SUMOpro 和 SUMOstar 在世界范围内被学术、政府、制药和生物技术实体所使用