

CatalogNo./Size: | GMH008A-025/25Tests GMH008A-100/100Tests | |
Vol.per.Test: | 10μl/Test | |
Clone: | Riv11 | |
Isotype: | MouseIgG1 | |
Reactivity: | Human,Notyettestedinotherspecies. | |
Workshop: | N/A | |
StorageBuffer: | Phosphate-bufferedsolution,pH7.4,containing0.09%sodiumazide | |
StorageCondition: | Storeat4�C.DONOTFREEZE.LIGHTSENSITIVEMATERIAL. | |
Applications: | FlowCytometry | |
ApplicationsNotes: | FACS:Use10µlfor106cells | |
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Description: | RiV11reactswiththe32kDaachainofCD8.ThismoleculeisexpressedontheTsuppressor/cytotoxiccellpopulation(whichcomprisesabout1/3oftheperipheralbloodTlymphocytestotalpopulation)andwithmostofthymocytes,aswellasasubsetofNKcells.CD8expressesaseitheraheterodimerwiththeCD8bchain(CD8ab)orasahomodimer(CD8aaorCD8bb).CD8actsasaco-receptorwithMHCClassIrestrictedTCRsinantigenrecognition.CD8functionisimportantforpositiveselectionofMHCClassIrestrictedCD8+TcellsduringTcelldevelopment. |