Avalanche^®-in vivo Transfection Reagent is extremely powerful for gene functional studies and RNA interference in vivo. This reagent was made by our proprietary formula whichinteracts with nucleic acids, and move into cells via endocytosis. In addition to efficientlytransporting nucleic acidsinto the cells, the formula is also able to lead to the protection of the nucleic acids from lysosomal degradation andthe efficient release of those nucleic acidsfrom lysosomes to ensure maximum function. Avalanche^®-in vivo has been proven to be able to perform the maximum delivery of DNA, shRNA, siRNA, or oligonucleotides into different organs in the body. No significant pro-inflammatory responses have been detected using this reagent. Avalanche^®-in vivo can be administered via various routes, such as intravenous, intraperitoneal, intratumoral injection, etc. Avalanche^®-in vivo Transfection Reagent is the best choice for delivering nucleic acids in vivo.

References:

1. Baghel KS, Tewari BN, Shrivastava R, Malik SA, Lone MU, et al. Macrophages promote matrix protrusive and invasive function of breast cancer cells via MIP-1β dependent upregulation of MYO3A gene in breast cancer cells. Oncoimmunology. 2016 Jul 15;5(7):e1196299. PubMed PMID: 27622050; PubMed Central PMCID: PMC5006911.
2. Shimoda H, Doi S, Nakashima A, Sasaki K, Doi T, Masaki T. Inhibition of the H3K4 methyltransferase MLL1/WDR5 complex attenuates renal senescence in ischemia reperfusion mice by reduction of p16INK4a. Kidney Int. 2019 Nov;96(5):1162-1175. doi: 10.1016/j.kint.2019.06.021. Epub 2019 Aug 1. PubMed PMID: 31570196.

Features:

• Efficient delivery of DNA, shRNA, siRNA or oligonucleotides in vivo
• 200 µl reagent for 20 transfections in mouse
• Efficient delivery to the lung, liver, kidney, and spleen, liver, pancreas and certain type of tumor via systemic administration
• Delivery via Multiple modes of administration in many species
• Avalanche^®-in vivo/nucleic acid conjugated complexes are stable in serum for 16h
• No detectable inflammatory responses
• Efficient siRNA and plasmid DNA delivery via direct subcutaneous tumor injection (multiple tumor types)
• Reproducible results
• Applicable for plasmid DNA/siRNA co-injection
• Developed and manufactured by EZ Biosystems LLC

EZ Biosystems™是转染和基因表达产品及服务的全球供应商。我们的工厂位于马里兰大学帕克分校校园附近。公司致力于开发细胞类型特异性转染试剂，创造了世界上最大的细胞类型特异性转染试剂，可以在最常用的细胞系和原代细胞上进行最有效的转染。   产品 货号 规格 价格 Human Astrocyte (HA, NHA) Avalanche™  Transfection Reagent  EZT-HA00-1 0.5 ml $455.00 Human Astrocyte (HA, NHA) Avalanche™ Transfection Reagent  EZT-HA00-1 1.5 ml $795.00 Beta-TC-6 Cell Avalanche™ Transfection  Reagent (mouse pancreatic cancer cell) EZT-BETA-1 0.5 ml $455.00 Beta-TC-6 Cell Avalanche™ Transfection  Reagent (mouse pancreatic cancer cell) EZT-BETA-1 1.5 ml $795.00 H9c2(2-1) Cell Avalanche™ Transfection Reagent EZT-H9C2-1 0.5 ml $455.00 H9c2(2-1) Cell Avalanche™ Transfection Reagent EZT-H9C2-1 1.5 ml $795.00 Cementoblast (OCCM-30 cell) Avalanche™ Transfection Reagent EZT-OCCM-1 0.5 ml $455.00 Cementoblast (OCCM-30 cell) Avalanche™ Transfection Reagent EZT-OCCM-1 1.5 ml $795.00 Hep 3B Cell Avalanche™ Transfection Reagent (human hepatocellular carcinoma cell) EZT-HEP3-1 0.5 ml $455.00 Hep 3B Cell Avalanche™ Transfection Reagent (human hepatocellular carcinoma cell) EZT-HEP3-1 1.5 ml $795.00 Hep G2 Cell Avalanche™ Transfection Reagent (human hepatocellular carcinoma cell)  EZT-HEPG-1 0.5 ml $455.00 Hep G2 Cell Avalanche™ Transfection Reagent (human hepatocellular carcinoma cell)  EZT-HEPG-1 1.5 ml $795.00 Hepa 1-6 Cell Avalanche™ Transfection Reagent (mouse hepatoma cell)  EZT-HEPA-1 0.5 ml $455.00 Hepa 1-6 Cell Avalanche™ Transfection Reagent (mouse hepatoma cell)  EZT-HEPA-1 1.5 ml $795.00 HepG2/C3A Cell Avalanche™ Transfection Reagent (human hepatocellular carcinoma cell) EZT-C3A0-1 0.5 ml $455.00 苏州蚂蚁淘代理EZ Biosystems™在中国的业务。试剂EZ Biosystems™代理北京，试剂EZ Biosystems™代理，EZ Biosystems™华东代理，EZ Biosystems™华北代理，EZ Biosystems™华中代理，EZ Biosystems™华南代理