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商品描述
DESCRIPTION:
Thapsigarginisthemostwidelyusedinhibitoroftheubiquitoussarco-endoplasmicreticulumCa2+-ATPasesinmammaliancells.Aguaianolidecompoundofplantorigin,ithasbecomeacommonlyusedresearchtoolintheelucidationofthemechanismsofintracellularCa2+signalling.
ItsremarkablepotencyandselectivityhavebeeninstrumentalindevelopingourunderstandingofthefunctionofintracellularCa2+stores,includingstore-operatedCa2+entryortheinvolvementofthestoresinproteinsynthesisorcellgrowth.
DATASHEET:
| Chemicalname | (3S,3aR,4S,6S,6aR,7S,8S,9bS)-6-(acetyloxy)-4-(butyryloxy)-3,3a-dihydroxy-3,6,9-trimethyl-8-{[(2Z)-2-methylbut-2-enoyl]oxy}-2-oxo-2,3,3a,4,5,6,6a,7,8,9b-decahydroazuleno[4,5-b]furan-7-yloctanoate |
| CASnumber | 67526-95-8 |
| Molecularweight | 650.8 |
| Formula | C34H50O12 |
| Solubility | SolubleinDMSOupto100mM |
| Purity | >98% |
| Storage | -20°C |
| Datasheet | A010-503 |
| Regulatorystatement | Productforresearchuseonly.Notintendedfordiagnosticortherapeuticuse. |
