absoluteantibody/Ab00151-10.0 Anti-Influenza A HA [HA]/Ab00151-10.0/ 100 µg

价格
¥8512.00
货号:Ab00151-10.0
浏览量:127
品牌:Absolute Antibody
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商品描述
Description:RecombinantmonoclonalantibodytoInfluenzaAHA.ManufacturedusingAbAb’sRecombinantPlatformwithvariableregions(i.e.specificity)fromtheEBVtransformedhumanBcellcloneHA.MadewithAntibodySequenceslicensedfromHumabsBiomedSA.MadewithAntibodySequenceslicensedfromHumabsBiomedSA.
SpeciesandIsotype:HumanIgG1,kappa
CloneNumber:HA
UniProtAccessionNumberofTargetProtein:
AlternativeName(s)ofTarget:haemagglutinin;hemagglutinin
PublishedApplication(s):ELISA
PublishedSpeciesReactivity:InfluenzaAVirus(severalsubtypes)
Immunogen:MadebyimmortalizingIgG-expressingBcellsfromindividualsfollowingvaccinationwithseasonalinfluenzavaccine,containingH1andH3influenzaVirussubtypes.
Specificity:ThisantibodyspecificallyrecognizestheconformationalepitopeinthestemregionofHAinwhichaminoacidsequencesarehighlyconservedinH1N1,H5N1,H6N1,andH9N2subtypesofInfluenzaAviruThisantibodyusestheVH1-69*01,D3-10*01,JH5*02,VL2D-29*02andJL4.ThisantibodydoesnotcrossreactwithHAinH2N2,H3N2andH7N7subtypeofInfluenzaAVirus.Thisantibodyhasnoeffectonhaemagglutination-inhibitionactivity.
AntibodyFirstPublishedin:
Corti,D.etal.Heterosubtypicneutralizingantibodiesareproducedbyindividualsimmunizedwithaseasonalinfluenzavaccine.JClinInvest120,1663–1673(2010).PMID:20389023Noteonpublication:DescribestheisolationandanalysisofapanelofhumanantibodiesfromvaccinatedindividualsanditsevaluationusingVirusneutralizationassays.

ProductForm

Purification:ProteinAaffinitypurified
Suppliedin:PBSwithpreservative(0.02%Proclin300)
StorageRecommendation:Storeat4°Cforupto3months.Forlongertermstoragealiquotintosmallvolumesandstoreat-20°C
Concentration:Seeviallabel.

Importantnote–Thisproductisforresearchuseonly.Itisnotintendedforuseintherapeuticordiagnosticproceduresforhumansoranimals. Absolute Antibody英国牛津大学Hutchings博士和Barclay教授创办的第二代抗体公司,可以在两周内提供100mg级的工程化抗体,并且没有动物成分,批间差很小,消除因补体和Fc受体造成的背景,使结果更干净。该公司的成立顺应了Nature杂志为首的科学界提倡改变目前抗体供应混乱状况的时代潮流。