绝对抗体/Ab00692-1.1抗埃博拉核蛋白[KZ51]/Ab00692-1.1/200µg

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¥6384.00
货号:Ab00692-1.1
浏览量:127
品牌:Absolute Antibody
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商品描述
Description:RecombinantmonoclonalantibodytoEbolaNucleoprotein.ManufacturedusingAbAb’sRecombinantPlatformwithvariableregions(i.e.specificity)fromthephagedisplayantibodyKZ51.
SpeciesandIsotype:MouseIgG1,kappa
CloneNumber:KZ51
UniProtAccessionNumberofTargetProtein:
PublishedApplication(s):ELISA;WB;IP;IF
PublishedSpeciesReactivity:EbolaVirus(Zaire,IvoryCoast,Reston,Sudan)
Immunogen:ThisantioBDywasderivedfromahumansurvivorofthe1995KikwitoutbreakofEbola.
Specificity:ThisantibodybindstothenucleoproteinoffourEbolavirusstrainsandhasaspecificityfoundinconvalescentpatients.Nocross-reactivitywithotherproteins(e.g.GP)wasdetectedbyrADIoimmunoprecipitation.
ApplicationNotes:Thisantibodyisbroadlycross-reactingbetweendifferentEbolastrainsandcompeteswithantibodiesnaturallyoccuringincovalescentpatients.ByIF,thisantibodyhashigherreactivitytowardsfixedvirusthantolivevirus-thoughbothmaybedetected.Ithasalsobeenusedasapositivecontrolinthedevelopmentofanti-Ebolapolyclonalgoatantibodies(Boisenetal.2015).
AntibodyFirstPublishedin:
Maruyamaetal.Ebolaviruscanbeeffectivelyneutralizedbyantibodyproducedinnaturalhumaninfection.JVirol.1999Jul;73(7):6024–6030.PMID:12350354Noteonpublication:Describesthegenerationandfunctionalcharacterizationofthisantibody.

ProductForm

Purification:ProteinAaffinitypurified
Suppliedin:PBSwithpreservative(0.02%Proclin300)
StorageRecommendation:Storeat4°Cforupto3months.Forlongertermstoragealiquotintosmallvolumesandstoreat-20°C
Concentration:Seeviallabel.

Importantnote–Thisproductisforresearchuseonly.Itisnotintendedforuseintherapeuticordiagnosticproceduresforhumansoranimals. Absolute Antibody英国牛津大学Hutchings博士和Barclay教授创办的第二代抗体公司,可以在两周内提供100mg级的工程化抗体,并且没有动物成分,批间差很小,消除因补体和Fc受体造成的背景,使结果更干净。该公司的成立顺应了Nature杂志为首的科学界提倡改变目前抗体供应混乱状况的时代潮流。