绝对抗体/Ab00696-1.1抗MERS冠状病毒棘突蛋白[D12]/Ab00696-1.1/200µg

价格
¥6384.00
货号:Ab00696-1.1
浏览量:127
品牌:Absolute Antibody
服务
全国联保
正品保证
正规发票
签订合同
商品描述
Description:RecombinantmonoclonalantibodytoMERS-CoVSpikeProtein.ManufacturedusingAbAb’sRecombinantPlatformwithvariableregions(i.e.specificity)fromthehybridomaD12.
SpeciesandIsotype:MouseIgG1,kappa
CloneNumber:D12
UniProtAccessionNumberofTargetProtein:
PublishedApplication(s):NTRL;ELISA;Crystallization;IF
PublishedSpeciesReactivity:MERS-CoV
Immunogen:MERS-CoV(England1strain)S1protein.
Specificity:ThisantibodybindstoMERS-CoVspikeproteinreceptorbindingdomainontheS1protein.Itisreportedtocross-reactswithMERS-CoVstrainsEngland1,Bishan1,England1-D509G,whilstbindingtoEngland1-S532P,W535RandE536Risimpaired.
ApplicationNotes:ThisantibodybindstoMERS-spikeproteinreceptorbindingdomain,andhasneutralizingeffectinaninvitromodelandwaselicitedbyavaccineconferringlong-lastinginvivoprotection.ThisantibodydoesnotworkbyWesternBlot.
AntibodyFirstPublishedin:
Wangetal.EvaluationofcandidatevaccineapproachesforMERS-CoVNatCommun6,7712(2015)PMID:26218507Noteonpublication:Describesthegenerationaswellasfunctionalandstructuralcharacterizationofthisantibody.

ProductForm

Purification:ProteinAaffinitypurified
Suppliedin:PBSwithpreservative(0.02%Proclin300)
StorageRecommendation:Storeat4°Cforupto3months.Forlongertermstoragealiquotintosmallvolumesandstoreat-20°C
Concentration:Seeviallabel.

Importantnote–Thisproductisforresearchuseonly.Itisnotintendedforuseintherapeuticordiagnosticproceduresforhumansoranimals. Absolute Antibody英国牛津大学Hutchings博士和Barclay教授创办的第二代抗体公司,可以在两周内提供100mg级的工程化抗体,并且没有动物成分,批间差很小,消除因补体和Fc受体造成的背景,使结果更干净。该公司的成立顺应了Nature杂志为首的科学界提倡改变目前抗体供应混乱状况的时代潮流。