品牌分类
品牌咨询
- CD4 Monoclonal Antibody (RM45), PE, eBioscience
- bpsbioscience常备现货
- 求教:BPS Bioscience官网 BPS Bioscience经销商/代理商,是假货吗?
- BPS bioscience代理_上海elisa生物技术有限公司
- GABAA Receptor β2 Subunit Polyclonal Antibody
- bpsbioscience抗体产品手机版
- 【Bpsbioscience代理】_上海酶联生物
- Antibodies, Proteins, Kits and Reagents for Life Science ...
- BRD4 (BD1) Inhibitor Screening Assay Kit性能参数,报价/价格,图片...
- BPS BioscienceELISA 试剂盒
- mysql源码安装_zengzehui的专栏
- BPS bioscience_BPS bioscience
联系方式
公司地址
苏州工业园区生物纳米园A4#216
联系电话
4000-520-616 / 18915418616
传真号码
0512-67156496
电子邮箱
info@ebiomall.com
公司网址
https://www.ebiomall.com
商品描述
Species: Human
Host Species: Sf9 insect cells
MW: 98 kDa
Genbank #: NM_014920
Tag(s): N-terminal GST-tag
a.a: full length
Background:
ICK or intestinal cell kinase belongs to a very extensive family of proteins that share a conserved catalytic core common with both serine/threonine and tyrosine protein kinases. ICK encodes an intestinal serine/threonine kinase harboring a dual phosphorylation site found in mitogen-activating protein (MAP) kinases (1). ICK localizes to the intestinal crypt region and is thought to be important in intestinal epithelial cell proliferation and differentiation. ICK purified from transfected human embryonic kidney cells undergoes autophosphorylation and phosphorylates a test protein. ICK plays a key role in development of central nervous, skeletal, and endocrine systems (2).
Description:
Recombinant human intestinal cell kinase (ICK), full length, with N-terminal GST-tag, expressed by Sf9 insect cells via a baculovirus expression system.
Synonym(s):
ECO; MRK; KIAA0936; LCK2; MGC46090
Purity:
≥75%
Formulation:
50 mM Tris-HCl, pH 7.5, 150 mM NaCl, 10 mM glutathione, 0.1 mM EDTA, 0.25 mM DTT, 0.1 mM PMSF, 25% glycerol.
Format:
Aqueous buffer solution
Storage / Stability:
>6 months at -80°C.
Application(s):
Useful for the study of enzyme kinetics, screening inhibitors, and selectivity profiling.
Reference(s):
1. Togawa, K. et.al: Intestinal cell kinase (ICK) localizes to the crypt region and requires a dual phosphorylation site found in map kinases. J. Cell. Physiol. 183: 129-139, 2000.
2. Lahiry, P. et.al: A multiplex human syndrome implicates a key role for intestinal cell kinase in development of central nervous, skeletal, and endocrine systems.
2. Lahiry, P. et.al: A multiplex human syndrome implicates a key role for intestinal cell kinase in development of central nervous, skeletal, and endocrine systems.
Warning(s):
Avoid freeze/thaw cycles
Scientific Category:
Kinase/Serine-Threonine
Product Type:
Recombinant Protein
Data shown is lot-specific. Contact us for specific information on other lots.
