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蚂蚁淘在线 / 品牌中心 / avanti polar lipids / avanti polar lipids/Nordeoxycholic acid/5mg/700240P-5mg

avanti polar lipids/Nordeoxycholic acid/5mg/700240P-5mg

价格
￥3275.00
货号：700240P-5mg
浏览量：127
品牌：avanti polar lipids
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商品描述

700240 | Nordeoxycholic acid

23-nor-5β-cholanoic acid-3α, 12α-diol

Nordeoxycholic acid
Info

Nordeoxycholic acid

23-nor-5β-cholanoic acid-3α, 12α-diol

Nordeoxycholic Acid also known as 23-Nor-Deoxycholic Acid (23-Nor-DCA) is a steroid human metabolite with higher serum levels in women compared to men.

It’s a relative of the bile acid (BA) norcholic acid and a 23-carbon derivative of deoxycholic acid (DCA).

Norcholic acid is a minor BA found predominantly in human urine and meconium, while deoxycholic acid is one of the secondary BAs and an end product of the intestinal bacteria.

All BAs are important biomolecules, synthesized in the liver from cholesterol catabolism and responsible for the normal digestion and absorption of fats and other sterols. However, under certain pathological conditions, certain BAs can become prominent, and tend to show toxic effects on cells and tissues.

Levels of Norcholic acid, for instance, are increased in patients with cirrhosis and xanthomatosis - a metabolic disorder, characterized by mitochondrial enzyme sterol 27-hydrolase (CYP27A1) deficiency, that leads to progressive neurological symptoms.

As for the other parent compound of Nordeoxycholic Acid, DCA, it’s a BA with numerous effects in the human body, including emulsification of fats, preventing and dissolving gallstones, adipocytes destruction, and more.

As a BA, Nordeoxycholic Acid has similar effects, and it has also been found to decrease in models of rats on a high-fat diet, with a nonalcoholic fatty acid liver disease.

Additionally, Nordeoxycholic Acid is widely used as an internal standard for the quantification of bile acids.

Avanti’s Nordeoxycholic Acid is a high-quality bile acid for use in various types of bioanalyses research.

Data
Hygroscopic
No
Light Sensitive
No
Molecular Formula

C23H38O4

Percent Composition

C 72.98%, H 10.12%, O 16.91%

Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
53608-86-9 CAS Registry Number is a Registered Trademark of the American Chemical Society
FormulaWeight
378.55
Exact Mass
373.28
Downloads
  • ChemDraw File
  • 3D Structure
  • Structure
  • Safety Data Sheet
References
Certificates of Analysis
  • Certificate of Analysis(Lot No. 700240P-5MG-A-010and 6838PHA010)
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美国Avanti Polar Lipids Inc www.avantilipids.com Avanti Polar Lipids Inc, 是美国著名的磷脂类产品的生产商，该公司主要为各种制药厂和研究机构提供从毫克级到公斤级乃至吨级的磷脂类和甾体类中间体和试剂。 Avanti Polar Lipids.公司为世界范围内的研究机构和制药公司提供 1000 种以上脂类产品,由于其产品的高纯度而享誉全球, For 40 years, Avanti Polar Lipids, Inc. has been supplying lipids to researchers and pharmaceutical companies around the world. Not only has the range of products grown every year but so has Avanti’s unique reputation for purity. This brings us the satisfaction of our clients and the envy of our competitors. Avanti’s clients order from a stock of over 1,000 lipids at affordable prices. They enjoy working with our dedicated Customer Service representatives and benefit from our informed Technical Support team. Research clients are encouraged to contact us about custom synthesis of products not listed in our catalog. We are pleased to offer our Pharmaceutical clients products which follow cGMP guidelines. Avanti’s selection of chemicals and range of services for Research and Pharmaceutical applications include • Analytical Services • Bioactive Lipids • Biotinylated Lipids • Cationic Lipids • L-threo-Lac Cer (Caveolar Uptake Inhibitor) • Cholesterol, Plant & Animal Derived • Coenzyme A, Fluorescent & Fatty Acyl Derivatives • Deuterium Labeled Phospholipids & Sphingolipids • Eicosanoids (synthetic) • Extrusion Equipment for Liposome Preparation • Fluorescent Phospholipids & Sphingolipids • Glycosylated & Phosphorylated Sphingolipids • Kdo2 Lipid A (TLR 4 Agonist) • PHAD™ Synthetic Vaccine Adjuvant • Lipid Formulation • LPA, Cyclic LPA & LPA Analogues • LIPID MAPS Mass Spec Standards • Oxidized Lipids • Sterols, Oxysterols, Deuterated & Fluorescent Sterols • PIP’s, Polyunsaturated PIP3, & Fluorescent PIP’s • Phospholipids & Sphingolipids • Polymerizable Lipids, PEG-Lipids & Functionalized PEG’s • Prostaglandins (synthetic) • S1P/LPA Receptor Selective Agonists & Antagonists • Sphingosyl PE & PI