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蚂蚁淘在线 / 品牌中心 / avanti polar lipids / avanti polar lipids/DSPE-PEG(2000)-DBCO/25mg/880229P-25mg

avanti polar lipids/DSPE-PEG(2000)-DBCO/25mg/880229P-25mg

价格
￥8290.00
货号：880229P-25mg
浏览量：127
品牌：avanti polar lipids
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商品描述

880229 | DSPE-PEG(2000)-DBCO

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[dibenzocyclooctyl(polyethylene glycol)-2000] (ammonium salt)

DSPE-PEG(2000)-DBCO
Info

DSPE-PEG(2000)-DBCO

1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[dibenzocyclooctyl(polyethylene glycol)-2000] (ammonium salt)

Cu-free click chemistry with readily synthesized biarylazacyclooctynones. The reaction of azides with strained alkynes, such as cyclooctynes, readily forms a triazole product without the need for a toxic catalyst.
Refer also to DSPE-PEG Azide Avanti Number 880228

Representative Structure

The molecular weight and exact mass are averages based on the polydispersity of PEG.

Data
Hygroscopic
Yes
Light Sensitive
No
Molecular Formula

C151H279N4O56P (average MW due to polydispersity of PEG)

Percent Composition

C 58.93%, H 9.14%, N 1.82%, O 29.11%, P 1.01%

Purity
>99%
Stability
1 Year
Storage Temperature
-20°C
CAS Number
2052955-83-4 CAS Registry Number is a Registered Trademark of the American Chemical Society
FormulaWeight
3077.839
Exact Mass
3075.884
Synonyms
1,2-distearoyl-sn-glycero-3-phosphoethanolamine-N-[carbonyl-amino(polyethylene glycol)-2000-N’-(succinylazadibenzocyclooctyne)] (ammonium salt)
Downloads
  • ChemDraw File
  • 3D Structure
  • Structure
  • Safety Data Sheet
References

Wong P, Li L, Chea J, Hu W, Poku E, Ebner T, Bowles N, Wong JYC, Yazaki PJ, Sligar S, Shively JE. Antibody Targeted PET Imaging of 64Cu-DOTA-Anti-CEA PEGylated Lipid Nanodiscs in CEA Positive Tumors. Bioconjug Chem. 2020 Jan 30:10.1021/acs.bioconjchem.9b00854. doi: 10.1021/acs.bioconjchem.9b00854. Epub ahead of print. PMID: 31961138.

PubMed ID: 31961138

Umlauf BJ, Clark PA, Lajoie JM, Georgieva JV, Bremner S, Herrin BR, Kuo JS, Shusta EV. Identification of variable lymphocyte receptors that can target therapeutics to pathologically exposed brain extracellular matrix. Sci Adv. 2019 May 15;5(5):eaau4245. doi: 10.1126/sciadv.aau4245. eCollection 2019 May.

PubMed ID: 31106264

Gupta A, Shin JH, Lee MS, Park JY, Kim K, Kim JH, Suh M, Park CR, Kim YJ, Song MG, Jeong JM, Lee DS, Lee YS, Lee JS. Voxel-Based Dosimetry of Iron Oxide Nanoparticle-Conjugated 177Lu-Labeled Folic Acid Using SPECT/CT Imaging of Mice. Mol Pharm. 2019 Apr 1;16(4):1498-1506. doi: 10.1021/acs.molpharmaceut.8b01125. Epub 2019 Mar 18.

PubMed ID: 30821463

Jewett JC, Sletten EM, Bertozzi CR. Rapid Cu-free click chemistry with readily synthesized biarylazacyclooctynones. J Am Chem Soc. 2010 Mar 24;132(11):3688-90. doi: 10.1021/ja100014q.

PubMed ID: 20187640

Whitehead SA, McNitt CD, Mattern-Schain SI, Carr AJ, Alam S, Popik VV, Best MD. Artificial Membrane Fusion Triggered by Strain-Promoted Alkyne-Azide Cycloaddition. Bioconjug Chem. 2017 Apr 19;28(4):923-932. doi: 10.1021/acs.bioconjchem.6b00578. Epub 2017 Mar 14.

PubMed ID: 28248084
Certificates of Analysis
  • Certificate of Analysis(Lot No. 880229P-100MG-A-013and 6308PLA013)
  • Certificate of Analysis(Lot No. 880229P-10MG-A-013and 6308PIA013)
  • Certificate of Analysis(Lot No. 880229P-25MG-A-013and 6308PJA013)
  • Certificate of Analysis(Lot No. 880229P-50MG-A-013and 6308PKA013)
  • Certificate of Analysis(Lot No. 880229P-10MG-A-014and 6308PIA014)
  • Certificate of Analysis(Lot No. 880229P-25MG-B-013and 6308PJB013)
  • Certificate of Analysis(Lot No. 880229P-50MG-B-013and 6308PKB013)
  • Certificate of Analysis(Lot No. 880229P-100MG-A-014and 6308PLA014)
  • Certificate of Analysis(Lot No. 880229P-25MG-A-014and 6308PJA014)
  • Certificate of Analysis(Lot No. 880229P-50MG-A-014and 6308PKA014)
  • Certificate of Analysis(Lot No. 880229P-10MG-B-014and 6308PIB014)
  • Certificate of Analysis(Lot No. 880229P-100MG-B-014and 6308PLB014)
  • Certificate of Analysis(Lot No. 880229P-10MG-C-014and 6308PIC014)
  • Certificate of Analysis(Lot No. 880229P-100MG-C-014and 6308PLC014)
  • Certificate of Analysis(Lot No. 880229P-25MG-A-015and 6308PJA015)
  • Certificate of Analysis(Lot No. 880229P-50MG-A-015and 6308PKA015)
  • Certificate of Analysis(Lot No. 880229P-25MG-B-015and 6308PJB015)
  • Certificate of Analysis(Lot No. 880229P-10MG-A-015and 6308PIA015)
  • Certificate of Analysis(Lot No. 880229P-10MG-C-015and 6308PIC015)
  • Certificate of Analysis(Lot No. 880229P-50MG-B-015and 6308PKB015)
  • Certificate of Analysis(Lot No. 880229P-50MG-C-015and 6308PKC015)
  • Certificate of Analysis(Lot No. 880229P-25MG-C-015and 6308PJC015)
  • Certificate of Analysis(Lot No. 880229P-50MG-D-015and 6308PKD015)
  • Certificate of Analysis(Lot No. 880229P-100MG-A-016and 6308PLA016)
  • Certificate of Analysis(Lot No. 880229P-100MG-B-016and 6308PLB016)
  • Certificate of Analysis(Lot No. 880229P-25MG-A-016and 6308PJA016)
  • Certificate of Analysis(Lot No. 880229P-10MG-B-016and 6308PIB016)
  • Certificate of Analysis(Lot No. 880229P-50MG-C-016and 6308PKC016)
  • Certificate of Analysis(Lot No. 880229P-25MG-B-016and 6308PJB016)
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美国Avanti Polar Lipids Inc www.avantilipids.com Avanti Polar Lipids Inc, 是美国著名的磷脂类产品的生产商，该公司主要为各种制药厂和研究机构提供从毫克级到公斤级乃至吨级的磷脂类和甾体类中间体和试剂。 Avanti Polar Lipids.公司为世界范围内的研究机构和制药公司提供 1000 种以上脂类产品,由于其产品的高纯度而享誉全球, For 40 years, Avanti Polar Lipids, Inc. has been supplying lipids to researchers and pharmaceutical companies around the world. Not only has the range of products grown every year but so has Avanti’s unique reputation for purity. This brings us the satisfaction of our clients and the envy of our competitors. Avanti’s clients order from a stock of over 1,000 lipids at affordable prices. They enjoy working with our dedicated Customer Service representatives and benefit from our informed Technical Support team. Research clients are encouraged to contact us about custom synthesis of products not listed in our catalog. We are pleased to offer our Pharmaceutical clients products which follow cGMP guidelines. Avanti’s selection of chemicals and range of services for Research and Pharmaceutical applications include • Analytical Services • Bioactive Lipids • Biotinylated Lipids • Cationic Lipids • L-threo-Lac Cer (Caveolar Uptake Inhibitor) • Cholesterol, Plant & Animal Derived • Coenzyme A, Fluorescent & Fatty Acyl Derivatives • Deuterium Labeled Phospholipids & Sphingolipids • Eicosanoids (synthetic) • Extrusion Equipment for Liposome Preparation • Fluorescent Phospholipids & Sphingolipids • Glycosylated & Phosphorylated Sphingolipids • Kdo2 Lipid A (TLR 4 Agonist) • PHAD™ Synthetic Vaccine Adjuvant • Lipid Formulation • LPA, Cyclic LPA & LPA Analogues • LIPID MAPS Mass Spec Standards • Oxidized Lipids • Sterols, Oxysterols, Deuterated & Fluorescent Sterols • PIP’s, Polyunsaturated PIP3, & Fluorescent PIP’s • Phospholipids & Sphingolipids • Polymerizable Lipids, PEG-Lipids & Functionalized PEG’s • Prostaglandins (synthetic) • S1P/LPA Receptor Selective Agonists & Antagonists • Sphingosyl PE & PI