Product name

451lLu BR Non-Viable Cell Pellet (5 x 10^6 cells)

Catalog number

451lLu BR-03-0005-A (5mg)

Description

Background : Non-viable cell pellet was generated from cell line 451ILu BR. 451ILu BR is a human metastatic melanoma cell line. This cell line is resistant to BRAF and MEK inhibitors. This cell line features the specific V600E (Val600Glu) mutation at codon 600 in the BRAF gene. This mutation causes constitutively active kinase activity and activation of MEK and ERK signaling pathway. This cell line was derived from the same patient as the cell lines, WM164, and 451Lu. 451ILu BR cells produce xenograft tumors when injected into immunocompromised mice.Application Note : Frozen non-viable cell pellets can be used for in vitro experiments such as Western blotting and other immunoassays, genomic DNA isolation, STR profiling, and RNA isolation.

Source

Rockland

Product category

Cells, Media & Fractions

Product sub category

Cell Lysates & RNA

Target species

Human

Shipment info

Dry Ice

Nacres Codification

NA.61

2018年今年，我们参加了许多会议，介绍了在实验室中执行的工作结果。从1月开始，我们在英国ESACT 2018会议上展示了一张海报，主题为`` 开发先进的3D文化模型以评估细胞反应 ''。4月，我们参加了在芝加哥举行的ACR会议，并发表了题为“ 在氧气控制条件下使用患者衍生的CRC微流体3D癌症模型对药物反应和侵袭能力进行时滞分析 ”的海报。在DECHEMA 3D细胞培养会议上，以“ 用于临床前筛查的高级生理相关3D模型”为主题，展示了另一张海报。这些海报展示了我们CellPhy的不同方面 提供，针对生理相关条件。今年5月，Isabelle Topin凭借在tebu-bio的蛋白质生产和纯化平台项目经理的经验，在波尔多举行的SBCN2018会议上发表了题为“ 更多和更好-不稳定蛋白的生产和纯化的创新技巧 ”的海报。实验室。11月，Joost Boex（tebu-bio荷兰大客户经理）参加了荷兰生物物理学会议，他在会议上展示了题为“ SiR探针-解密复杂3D细胞培养模型的简单方法 ”的海报，展示了SiR探针的高效率用于活细胞成像。