Overview:

STK21 is a serine/threonine-protein kinase that functions in cell division and also to promote efficient cytokinesis. STK21 is a novel molecular mechanism for a subset of human malformation syndromes of the central nervous system (1). STK21 is also associated with bipolar disorder and risk for schizophrenia. STK21 is a novel partner for the GTP-bound forms of rho and rac (2).

Gene Aliases:

CIT; CRIK

Genbank Number:

NM_007174

References:

1. Di Cunto, F.et.al: Citron Rho-interacting kinase, a novel tissue-specific ser/thr kinase encompassing the Rho-Rac-binding protein citron. J. Biol. Chem. 273: 29706-29711, 1998.2. Madaule, P.et.al: A novel partner for the GTP-bound forms of rho and rac. FEBS Lett. 377: 243-248, 1995.