- Peptide Substrates
- Binding Proteins
- Secondary Antibodies
- Regulatory proteins
- 脂类激酶
- 双加氧酶与蛋白质
- 脂质底物
- E2
- Assay Buffer and Co-factors
- Methyltransferases
- Acetyltransferases
- Transcription Proteins
- COVID-19 ELISA Kits
- Tau Proteins
- Microtubule & Actin Associated Proteins
- Carbohydrate Substrates
- COVID-19 Proteins
- Chemokines
- 标记抗体
- 授予称号
- E3
- 【桥头火锅】品牌介绍→桥头火锅底料_重庆桥头火锅_买购网
- SignalChem|生产厂家|价格信息
- signalchem
- IL4 Gene GeneCards | IL4 Protein | IL4 Antibody
- 代理产品SignalchemSignalchem
- 重组人IL11说明书
- cell signaling 三天审稿完毕,小修! 论文投稿 交流 ...
- ...SignalChem一级代理,SignalChem中国代理,SignalChem公司_环保...
- “不积极”英语是什么?unactive吗?
- “不积极”英语是什么?unactive吗?
- 苏州蚂蚁淘实验试剂有限公司17年8月份销售过的产品1苏州蚂蚁淘...
- SignalChem安徽代理 |产品目录|代理商|蚂蚁淘进口试剂平行进口
Overview:
Tau-441orTau-FisamemberoftheTaufamilyofproteinswhichfunctiontostABIlizethemicrotubulesbybindingtothem.TauproteinsaresubjecttophosphorylationandthisphenomenonregulatestheassociationoftheTauproteinwiththemicrotubules(1).DepositsofAlzheimer"sdiseaseAD-associatedproteins,suchashyperphosphorylatedTau,aswellasothersharedmisfoldedproteins,suchas,β-amyloidprecursorprotein(βAPP),ubiquitin,andvariouschaperonesandproteinkinasesarethoughttoplayapathologicroleinthecognitivedeclineandmuscularfailure.MalfunctioningofTauproteinsisassociatedwithmicrotubulesdisintegrationandcollapsingoftheneuronaltransportsystem(2).
GeneAliases:
Tau-F,(N2R4),Tau-4,MAPT,MSTD,PPND,DDPAC,MAPTL,MTBT1,MTBT2,FTDP-17,FLJ31424,MGC138549
GenbankNumber:
P10636-8
References:
1.Zilka,N.,etal.TruncatedtaufromsporADIcAlzheimer"sdiseasesufficestodriveneurofibrillarydegenerationinvivo.FEBSLett.2006;508:3582-3588.2.Rial,A.etal:CalciumDyshomeostasisinβ-AmyloidandTau-bearingSkeletalMyotubes.J.Biol.Chem.,2004;279:3524-53532.
