Overview:

GST or glutathione S-transferase family of enzymes comprises a long list of cytosolic, mitochondrial, and microsomal proteins that are used to create the so-called 'GST gene fusion system' (1). These proteins are capable of multiple reactions with a multitude of substrates.GST tag has the size of 220 amino acids, which is relatively big compared to other tags like the Myc- or theDYKDDDDK-tag that are quite small.GST can be used to purify and detect proteins of interest.

References:

1.Beckett, G.J. and Hayes, J.D. Glutathione S-transferase measurements and liver disease in man. J. Clin. Biochem. Nutr. 1987. 2, 1-24.